外科理论与实践2025，Vol.30Issue(6)：474-478,5.DOI:10.16139/j.1007-9610.2025.06.03
胰腺癌新辅助治疗若干问题思考:从循证医学到精准医疗的范式转换
Reflections on key issues in neoadjuvant therapy for pancreatic cancer:a paradigm shift from evidence-based medicine to precision medicine
摘要
Abstract
Neoadjuvant therapy for pancreatic cancer is undergoing a paradigm shift from conventional chemotherapy to precision medicine.This expert forum discussed cutting-edge issues in pancreatic cancer neoadjuvant therapy from an evidence-based perspective,incorporating the latest clinical research advances.We focused on innovative directions including immunotherapy combination strategies,liquid biopsy applications,artificial intelligence(AI)-assisted decision making,and individualized precision medicine.We proposed forward-looking concepts such as molecular subtyping-guided individualized treatment strategies,multi-omics integrated efficacy prediction models,and standardized multidisciplinary collaborative care systems.These innovative concepts will drive pancreatic cancer neoadjuvant therapy toward more precise and effective directions.关键词
胰腺癌/新辅助治疗/精准医疗/免疫治疗/液体活检/人工智能Key words
Pancreatic cancer/Neoadjuvant therapy/Precision medicine/Immunotherapy/Liquid biopsy/Artificial intelligence(AI)分类
医药卫生引用本文复制引用
康晓超,李轶楷,郭世伟,金钢..胰腺癌新辅助治疗若干问题思考:从循证医学到精准医疗的范式转换[J].外科理论与实践,2025,30(6):474-478,5.基金项目
上海市2023年度"科技创新行动计划"(23Y41900200) （23Y41900200）
