实用医学杂志2026，Vol.42Issue(3)：355-362,8.DOI:10.3969/j.issn.1006-5725.2026.03.001
静脉输注利多卡因治疗类风湿关节炎疼痛的机制与临床前景
Mechanisms and clinical prospects of intravenous lidocaine for pain management in rheumatoid arthritis
摘要
Abstract
Rheumatoid Arthritis(RA)is an autoimmune disease,with pain being its primary symptom.The mechanisms underlying RA pain involve both inflammatory and neuropathic components.Lidocaine,a classic amido-type local anesthetic,has gained widespread application in treating inflammatory and neuropathic pain due to its analgesic,anti-inflammatory,and immunomodulatory properties when administered intravenously.Given the exact match between the pathogenesis of RA pain and the pharmacological actions of intravenous lidocaine,this review explores the therapeutic potential of intravenous lidocaine infusion for RA pain.It aims to offer new insights into the clinical application of intravenous lidocaine for managing RA-related pain.关键词
类风湿关节炎/利多卡因/静脉内/炎症/神经病理性疼痛Key words
rheumatoid arthritis/lidocaine/intravenous/inflammation/neuropathic pain分类
医药卫生引用本文复制引用
吴婷,夏明忠,余相地..静脉输注利多卡因治疗类风湿关节炎疼痛的机制与临床前景[J].实用医学杂志,2026,42(3):355-362,8.基金项目
国家自然科学基金项目(编号:82060239) （编号:82060239）
