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蓝斑-去甲肾上腺素系统在注意中的作用机制

邢炼淄 陈玉洁 苗程菓 张阳

心理科学进展2026,Vol.34Issue(2):313-330,18.
心理科学进展2026,Vol.34Issue(2):313-330,18.DOI:10.3724/SP.J.1042.2026.0313

蓝斑-去甲肾上腺素系统在注意中的作用机制

The mechanisms of locus coeruleus-norepinephrine system in attention

邢炼淄 1陈玉洁 1苗程菓 1张阳1

作者信息

  • 1. 苏州大学心理学系,江苏 苏州 215000
  • 折叠

摘要

Abstract

The locus coeruleus-norepinephrine(LC-NE)system is a critical neuromodulatory system in the brain,playing an essential role in attentional modulation.This article provides a systematic review of the mechanisms by which the LC-NE system contributes to attention,including:1)the firing patterns and activity dynamics of the LC-NE during attentional processes;2)behavioral and neurophysiological indicators that reliably reflect LC-NE activity;3)the role of LC-NE in the three attentional subsystems—alerting,orienting,and executive control;4)the associations between LC-NE function and various attention-related disorders.Future studies should integrate techniques such as pupillometry,event-related potentials,intracranial electroencephalography,high-resolution neuroimaging,and neuromodulation.Combining these high spatiotemporal resolution tracking with causal intervention approaches can further elucidate the dynamic regulatory mechanisms of the LC-NE in attentional processing,thereby providing a theoretical basis for interventions on attentional disorders.

关键词

蓝斑-去甲肾上腺素系统/注意/警觉/定向/执行控制

Key words

LC-NE/attention/alerting/orienting/executive control

分类

社会科学

引用本文复制引用

邢炼淄,陈玉洁,苗程菓,张阳..蓝斑-去甲肾上腺素系统在注意中的作用机制[J].心理科学进展,2026,34(2):313-330,18.

基金项目

国家自然科学基金(32171049),江苏省社会科学基金(22JYB015),中国博士后科学基金(2024M752310),江苏省卓越博士后计划(20242B496). (32171049)

心理科学进展

1671-3710

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