中国内镜杂志2026，Vol.32Issue(1)：35-41,7.DOI:10.12235/E20250020
色素内镜和窄带成像技术联合放大内镜对早期结直肠癌及癌前病变的诊断价值研究
Study on the diagnostic value of chromoendoscopy and narrow-band imaging combined with magnifying endoscopy for early colorectal cancer and precancerous lesions
摘要
Abstract
Objective To explore the diagnostic value of the combination of chromoendoscopy(CE)and narrow-band imaging(NBI)with magnifying endoscopy(ME)for early colorectal cancer and precancerous lesions.Methods 160 patients with suspected early colorectal cancer and precancerous lesions from August 2023 to July 2024 were selected.The four-grid table method was adopted to analyze the sensitivity,specificity and accuracy of NBI-ME and CE-ME in detecting early colorectal cancer and precancerous lesions.The Kappa method was used to analyze the consistency of CE-ME and NBI-ME in the diagnosis of early colorectal cancer and precancerous lesions with pathological examination.Results The pathological results showed that there were 52 cases of benign lesions,90 cases of precancerous lesions and 18 cases of colorectal cancer.The CE-ME test results showed that there were 43 cases of benign lesions,101 cases of precancerous lesions,and 16 cases of colorectal cancer,with a misdiagnosis rate of 33.33%.The consistency of CE-ME in diagnosing early colorectal cancer and precancerous lesions with pathological examination was average(Kappa=0.605,P<0.01),with a sensitivity of 66.67%,a specificity of 97.18%,and an accuracy of 93.75%.The results of NBI-ME examination showed 43 cases of benign lesions,100 cases of precancerous lesions,and 17 cases of colorectal cancer.The misdiagnosis rate was 16.67%.The consistency of NBI-ME in diagnosing early colorectal cancer and precancerous lesions with pathological examination was relatively high(Kappa=0.714,P<0.01),and the sensitivity was 83.33%.The specificity was 98.59%and the accuracy was 96.88%.The combined examination results of CE-ME and NBI-ME showed that there were 56 cases of benign lesions,86 cases of precancerous lesions,and 18 cases of colorectal cancer.The misdiagnosis rate was 5.56%.The consistency of the combined diagnosis of early colorectal cancer and precancerous lesions with pathological examination was extremely good(Kappa=0.857,P<0.01).The sensitivity was 94.44%,the specificity was 99.30%,and the accuracy was 98.75%,which were higher than those of CE-ME and NBI-ME alone examinations.Conclusion The combination of CE and NBI with ME has a relatively high diagnostic value for early colorectal cancer and precancerous lesions.It is worth applying in clinical practice.关键词
色素内镜(CE)/窄带成像技术(NBI)/放大内镜(ME)/早期结直肠癌/癌前病变/诊断Key words
chromoendoscopy(CE)/narrow-band imaging(NBI)/magnifying endoscopy(ME)/early colorectal cancer/precancerous lesions/diagnosis分类
医药卫生引用本文复制引用
喻勤,彭昌能,罗志英..色素内镜和窄带成像技术联合放大内镜对早期结直肠癌及癌前病变的诊断价值研究[J].中国内镜杂志,2026,32(1):35-41,7.基金项目
湘南学院2023年度校级科研项目医院联合项目(No:2023XJ147) （No:2023XJ147）
湖南省自然科学基金项目(No:2025JJ70575) （No:2025JJ70575）
