摘要
Abstract
Objective To evaluate the clinical efficacy and technical aspects of percutaneous transhepatic choledochoscopic laser ablation and photodynamic therapy(PDT)in the treatment of mucinous cystic neoplasm of bile duct.Methods A retrospective analysis was conducted on 13 patients with mucinous cystic neoplasms of the bile duct treated between January 2018 and December 2023.All patients underwent treatment with percutaneous transhepatic choledochoscopic laser ablation,PDT,or a combination of both.Observe the surgery-related conditions of the patients,the lesion conditions,the drainage conditions,the survival status 6 months after the operation and the occurrence of complications.Results All patients successfully completed percutaneous transhepatic choledochoscopic laser ablation,PDT or a combination of both,with a treatment success rate of 100%.The body temperature of all patients returned to normal after the operation.Jaundice decreased in 7 patients within one week after the operation.In the remaining 6 patients,although jaundice did not decrease significantly,the total serum bilirubin decreased or remained stable.Within one week after the operation,the neoplasms in each branch of the bile duct of all patients decreased,and the lesions shrank significantly.In the early postoperative period(within 30 days),the drainage tubes of all patients remained unobstructed,and no acute tube blockage events caused by tumor tissue shedding or necrotic substances occurred.The average indwelling time of the drainage tube after the operation was 4.2 months.Six months after the operation,there were no deaths and the 6-month survival rate was 100%.No serious complications such as biliary perforation and massive hemorrhage occurred.Conclusion Percutaneous choledochoscopic laser ablation combined with PDT for the treatment of mucinous cystic tumors of the bile duct can reduce the lesion range,relieve biliary obstruction,improve the quality of life of patients,and has few complications.It is worthy of clinical promotion and application.关键词
胆管黏液性囊性肿瘤/激光消融术/光动力疗法(PDT)/胆道镜Key words
mucinous cystic neoplasm of bile duct/laser ablation/photodynamic therapy(PDT)/choledochoscopy分类
医药卫生
