Abstract
Objective To analyze the demographic characteristics,return donation patterns,and risk of adverse reac-tions among donors temporarily deferred due to blood pressure abnormalities,so as to provide an evidence-based foundation for optimizing pre-donation blood pressure screening strategies,enhancing donor retention,and ensuring blood supply safe-ty.Methods Data from 2.939 million donor instances were collected through the Information Management System at the Beijing Red Cross Blood Center between January 2015 and August 2025.The analysis specifically focused on the 11 600 in-stances of donors temporarily deferred due to abnormal blood pressure,examining demographic characteristics(age,and gender)and donation-related features(number of donations,donation site,and type of donation).Further analysis was conducted on the return donation patterns,including the return rate,time interval to return,and the incidence,type,and severity of adverse reactions among returned donors.Results Distribution of abnormal blood pressure:Among the 11 600 instances of abnormal blood pressure,the prevalence was significantly higher in males(0.48%,10 111/2 086 909)than in females(0.17%,1 465/852 090).The 46-55 age group had the highest prevalence(0.88%,2 925/329 235),and the differences across age groups were statistically significant.The prevalence was,higher among repeat donors(0.41%,5 242/1 276 452)than first-time donors(0.38%,6 334/1 662 547).The prevalence at mobile donation sites outside the blood center(0.06%,350/596 104)was higher than fixed donor centers(0.50%,10 225/2 052 290)and group donation drives(0.34%,1 001/290 608).Return donations:A total of 19.49%(2 256 out of 11 576)deferred donors returner and suc-cessfully donated.Among these donors,36.17%(816 out of 2 256)returned within 7 days,while the highest proportion of returns was observed within 31-182 days(25.44%,574/2 256).A higher return rate was observed among male donors(20.17%,2 039/1 0111)compared to female donors(14.81%,217/1 465).The return rate for repeat donors(43.02%,2 255/5 242)was significantly higher than that of first-time donors(0.02%,1/6 334).Individual donors showed a higher return rate(20.95%,1 986/9 479)than group donors(12.88%,270/2 097),with all differences being statistically significant(P<0.05).The differences in return rates across age groups were not statistically significant(P>0.05).Adverse reactions:The incidence of adverse reactions after return was 0.09%(2/2 256),significantly lower than the overall adverse reaction incidence during the same period(0.20%,5 981/2 938 999).Both adverse reactions were local reaction(category A1,pain or bruising at the puncture site),with no reported cases of systemic vasovagal reactions(VR)or severe adverse events.Conclusion The current blood pressure screening criteria may lead to the unnecessary deferral of eligible donors.The risk of adverse reactions is extremely low among returned donors who were deferred for abnormal blood pressure.A relaxation of the blood pressure screening criteria is therefore suggested,coupled with the optimization of dona-tion site environment and blood pressure measurement procedure with reference to expert consensus to enhance donor reten-tion and blood supply safety.关键词
血压不合格/返回献血/献血不良反应/影响因素Key words
abnormal blood pressure/return to blood donation/blood donation adverse reactions/influencing factors分类
医药卫生
