中国中西医结合影像学杂志2026，Vol.24Issue(1)：70-74,85,6.DOI:10.3969/j.issn.1672-0512.2026.01.014
血管斑块特征及脂肪衰减指数对冠心病心肌缺血的预测价值
Predictive value of plaque characteristics and fat attenuation index for myocardial ischemia in coronary heart disease
摘要
Abstract
Objective:To explore the predictive value of plaque characteristics and pericoronal fat attenuation index(FAI)in the diagnosis of myocardial ischemia in coronary heart disease.Methods:A retrospective analysis was performed on 265 patients with coronary heart disease(398 coronary arteries).And the plaque characteristics,the proximal FAI of the three main coronary arteries and CT fractional flow reserve(CT-FFR)were measured.The patients were divided into the myocardial ischemia group(91 cases,CT-FFR≤0.8)and non-myocardial ischemia group(174 cases,CT-FFR>0.8)according to CT-FFR values.Logistic regression analysis was used to evaluate the independent predictors of myocardial ischemia in coronary heart disease.The ROC curves were plotted to analyze the performance of the independent predictors on myocardial ischemia in coronary heart disease.Results:There was a statistically significant difference in the proportion of diabetes between the two groups(P<0.05).The myocardial ischemia group showed a longer lesion,more severe degree of coronary artery stenosis,more obvious degree of the positive remodeling,larger volume of plaque and calcification,a larger FAI,and a larger proportion of low-density plaques compared to the non-myocardial ischemia group(all P<0.05).Univariate and multivariate logistic regression analysis revealed that diabetes,degree of coronary artery stenosis and FAI were the independent predictors of myocardial ischemia in coronary heart disease(all P<0.05).ROC curve analysis showed that the AUC values for diagnosing myocardial ischemia in coronary heart disease by diabetes,degree of coronary artery stenosis and FAI were 0.564,0.812 and 0.708,respectively,and the AUC for the combined diagnosis was 0.850.Conclusion:Diabetes mellitus,stenosis degree and FAI have good predictive value in the diagnosis of myocardial ischemia in coronary heart disease.关键词
体层摄影术,X线计算机/血流储备分数/脂肪衰减指数/心肌缺血/冠心病Key words
Tomography,X-ray computed/Fraction flow reserve/Fat attenuation index/Myocardial ischemia/Coronary disease分类
医药卫生引用本文复制引用
郝秀秀,李旭,余广海,胡献阔,张磊,袁玉山,张杨..血管斑块特征及脂肪衰减指数对冠心病心肌缺血的预测价值[J].中国中西医结合影像学杂志,2026,24(1):70-74,85,6.基金项目
中国红十字基金会领航菁英科研项目(XM_HR_YXFN_2021_05_19) （XM_HR_YXFN_2021_05_19）
阜阳市卫健委科研课题青年项目(FY2021-010). （FY2021-010）
