中医正骨2025,Vol.37Issue(12):21-26,31,7.
数字健康技术辅助的康复疗法治疗膝骨关节炎效果的Meta分析
Efficacy of digital health technology-assisted rehabilitation therapy for treatment of knee osteoarthritis:a meta-analysis
摘要
Abstract
Objective:To systematically review the therapeutic efficacy of digital health technology(DHT)-assisted rehabilitation thera-py in treatment of knee osteoarthritis(KOA).Methods:All the randomized controlled trial(RCT)articles about the clinical outcomes of DHT-assisted rehabilitation therapy versus conventional rehabilitation therapy for treatment of KOA included from database's inception to January 2025 were retrieved from the China National Knowledge Infrastructure,Wanfang Database,Vip Database,Chinese Biomedical Literature Service System,PubMed,Embase,Web of Science and Cochrane Library.The pertinent articles were screened,the information was extracted and the risk of bias of the included researches in the articles was assessed independently by two researchers,and then a Meta-analysis was conducted using the Meta package in R software(version 4.4.1).Results:Seventeen articles(1049 KOA patients)were in-cluded in the final analysis,comprising both general KOA patients and post-total knee arthroplasty(TKA)KOA patients.The meta-analysis revealed that,compared to the conventional rehabilitation therapy,the DHT-assisted rehabilitation therapy significantly reduced patient's knee pain numerical rating scale(NRS)score and Western Ontario and McMaster Universities osteoarthritis index(WOMAC)score(TKA patients:SMD=-0.71,95%CI(-1.31,-0.12),P=0.018;general KOA patients:SMD=-0.60,95%CI(-0.77,-0.42),P=0.000;TKA patients:SMD=-0.55,95%CI(-1.08,-0.01),P=0.047;general KOA patients:SMD=-1.19,95%CI(-2.17,-0.21),P=0.017).Furthermore,the DHT-assisted rehabilitation therapy demonstrated superior efficacy in reducing timed up-and-go test duration compared to the conventional rehabilitation therapy in post-TKA KOA patients(SMD=-0.60,95%CI(-1.17,-0.04),P=0.037),while,the two therapies are comparable in improving this outcome in general KOA patients(SMD=-0.10,95%CI(-0.39,0.20),P=0.513).Moreover,the two therapies showed comparable therapeutic effect in improving knee range of motion in post-TKA KOA patients(SMD=0.46,95%CI(-0.02,0.93),P=0.061),while,only one study focused on general KOA patients,so no pooled analysis was con-ducted.The publication bias was analyzed based on the knee pain NRS score,and the result of Egger's test showed that there was no publi-cation bias in the included articles(P=0.078).Conclusion:Available evidences suggest that the DHT-assisted rehabilitation therapy is su-perior to the conventional rehabilitation therapy in alleviating knee pain and improving knee function in KOA patients.关键词
骨关节炎,膝/数字健康/康复/专题Meta分析Key words
osteoarthritis,knee/digital health/rehabilitation/meta-analysis as topic引用本文复制引用
蓝相洲,李铃佳,唐燕,贾庆,何芳颐,邝高艳,陈青,郭城..数字健康技术辅助的康复疗法治疗膝骨关节炎效果的Meta分析[J].中医正骨,2025,37(12):21-26,31,7.基金项目
国家中医优势专科(护理学)建设项目(国中医药医政函[2024]90号) (护理学)
湖南省自然科学基金项目(2024JJ9424) (2024JJ9424)
湖南省科技创新计划项目(2024RC3203) (2024RC3203)
湖南中医药大学校院联合重点项目(2023XYLH008) (2023XYLH008)