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Brain network predictors of changes in symptoms and serum BDNF following antidepressant treatment with escitalopram and Yueju Pill in major depressive disorder:a randomised,double-blind,placebo-controlled pilot study

Yuxuan Zhang Yiwei Ren Gang Chen Haosen Wang Jinlin Miao Bo Cui Zhilu Zou Jin Feng Chunkou Hong Mingzhi Han Jinhui Wang

General Psychiatry2025，Vol.38Issue(5)：P.335-347,13.

General Psychiatry2025，Vol.38Issue(5)：P.335-347,13.DOI:10.1136/gpsych-2025-102041

Brain network predictors of changes in symptoms and serum BDNF following antidepressant treatment with escitalopram and Yueju Pill in major depressive disorder:a randomised,double-blind,placebo-controlled pilot study

Yuxuan Zhang ¹Yiwei Ren ²Gang Chen ³Haosen Wang ⁴Jinlin Miao ⁴Bo Cui ⁵Zhilu Zou ⁶Jin Feng ⁴Chunkou Hong ⁴Mingzhi Han ⁵Jinhui Wang⁷

作者信息

1. Interdisciplinary Institute for Personalized Medicine in Brain Disorders,School of Chinese Medicine,Jinan University,Guangzhou,Guangdong,China School of Clinical Medicine,Yangzhou Polytechnic University,Yangzhou,Jiangsu,China
2. Institute for Brain Research and Rehabilitation,South China Normal University,Guangzhou,Guangdong,China
3. Interdisciplinary Institute for Personalized Medicine in Brain Disorders,School of Chinese Medicine,Jinan University,Guangzhou,Guangdong,China Zhuhai Institute of Jinan University,Zhuhai,Guangdong,China Guangdong-Hong Kong-Macao Joint Laboratory of Traditional Chinese Medicine on Brain-Peripheral Homeostasis and Comprehensive Health,Jinan University,Guangzhou,Guangdong,China Departments of Psychiatry&Clinical and Translational Institute of Psychiatric Disorders,First Affiliated Hospital of Jinan University,Guangzhou,Guangdong,China
4. The Fourth People''s Hospital of Taizhou,Taizhou,Jiangsu,China
5. Interdisciplinary Institute for Personalized Medicine in Brain Disorders,School of Chinese Medicine,Jinan University,Guangzhou,Guangdong,China
6. Hubei University of Chinese Medicine,Wuhan,Hubei,China
7. Institute for Brain Research and Rehabilitation,South China Normal University,Guangzhou,Guangdong,China Key Laboratory of Brain,Cognition and Education Sciences(South China Normal University),Ministry of Education,Guangzhou,Guangdong,China Center for Studies of Psychological Application,South China Normal University,Guangzhou,Guangdong,China Guangdong Key Laboratory of Mental Health and Cognitive Science,South China Normal University,Guangzhou,Guangdong,China Philosophy and Social Science Laboratory of Reading and Development in Children and Adolescents(South China Normal University),Ministry of Education,Guangzhou,Guangdong,China
折叠

摘要

关键词

major depressive disorder mdd/Gyrification Index/magnetic resonance imaging mri offers/yueju pill/Escitalopram/yueju pilla/Major Depressive Disorder/Brain Network

分类

医药卫生

引用本文复制引用

Yuxuan Zhang,Yiwei Ren,Gang Chen,Haosen Wang,Jinlin Miao,Bo Cui,Zhilu Zou,Jin Feng,Chunkou Hong,Mingzhi Han,Jinhui Wang..Brain network predictors of changes in symptoms and serum BDNF following antidepressant treatment with escitalopram and Yueju Pill in major depressive disorder:a randomised,double-blind,placebo-controlled pilot study[J].General Psychiatry,2025,38(5):P.335-347,13.

基金项目

supported by the National Key Research and Development Program of China(No.2022YFE0201000) （No.2022YFE0201000）

National Natural Science Foundation of China(Nos.82472092,82174002,81874374 and 81673625) （Nos.82472092,82174002,81874374 and 81673625）

a grant from the Research Center for Brain Cognition and Human Development,Guangdong,China(No.2024B0303390003) （No.2024B0303390003）

Key Realm R&D Program of Guangzhou(No.202206010109) （No.202206010109）

Taizhou Science and Technology Support Program(Social Development)project(No.TS2016-12). （Social Development）

General Psychiatry

ISSN：2096-5923

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