高等学校化学学报2026，Vol.47Issue(2)：27-35,9.DOI:10.7503/cjcu20250289
Fe-N共掺杂碳量子点作为高活性类过氧化物酶用于绿原酸比色检测
Fe-N co-Doped Carbon Quantum Dots as Highly Active Peroxidase Mimics for Colorimetric Detection of Chlorogenic Acid
摘要
Abstract
Fe-N-CDs nanopaticles were successfully prepared by one-step hydrothermal method using L-histidine and Fersulfate heptahydrate(FeSO₄·7H₂O)as precursors.The introduction of Fe atoms produced more active sites on the surface of carbon dots,promoted the electron transfer in the catalytic process,and thus improved the catalytic efficiency of the material.The Fe-N-CDs nanopaticles effectively catalyzed the decomposition of hydrogen peroxide(H2O2)to generate hydroxyl radicals(•OH),which subsequently oxidized 3,3',5,5'-tetramethylbenzidine(TMB)to form a blue oxidation product(oxTMB)with a characteristic absorption peak at 652 nm.Curcumin,a natural polyphe-nolic compound widely found in plants,exhibits excellent antioxidant properties and antidepressant effects.Leveraging the ability of curcumin to reduce oxTMB and cause its color to fade,a quantitative relationship between the change in absorbance and the curcumin content was established.This enabled the development of a colorimetric sensing method for the detection of curcumin.The experimental results demonstrated that this method possesses good selectivity,anti-interference capability and rapid response characteristics.It can be applied for the colorimetric analysis of antioxidant components in pharmaceuticals and food products,offering a new analytical approach for quality assessment of related products and the development of antidepressant drugs.关键词
碳点/纳米酶/绿原酸/比色检测Key words
Carbon dots/Naoeezymes/Chlorogenic acid/Colorimetric detection分类
化学化工引用本文复制引用
张敏,张文皓,李光英,王丽敏,单桂晔..Fe-N共掺杂碳量子点作为高活性类过氧化物酶用于绿原酸比色检测[J].高等学校化学学报,2026,47(2):27-35,9.基金项目
国家自然科学基金(批准号:1257041767)和吉林省自然科学基金(批准号:20200201582JC)资助. Supported by the National Natural Science Foundation of China(No.1257041767)and the Natural Science Foundation of Jilin Province,China(No.20200201582JC). （批准号:1257041767）
