日用化学品科学2026，Vol.49Issue(2)：26-33,8.DOI:10.3969/j.issn.1006-7264.2026.02.006
一款具有选择性清洁能力的双管洁面产品的评价方法研究
Evaluation method for a dual-chamber facial cleanser with selective cleansing ability
张文荣 1唐莉凤 1李雪玩 1郭亚玲 1周紫燕 1叶理2
作者信息
- 1. 广州稀咖科技有限公司,广东 广州 510000
- 2. 南方医科大学皮肤病医院,广东 广州 510091
- 折叠
摘要
Abstract
A method to evaluate the selective cleansing ability of a dual-chamber facial cleanser on human sebum was established.In vitro testing was performed using leather as a skin model to quantify the removal rate of squalene hydroperoxide and the retention rate of cholesterol for four facial cleanser products.A non-invasive assessment was conducted with 30 subjects with oily skin,measuring squalene hydroperoxide levels before and after cleansing,as well as changes in skin sebum content and transepidermal water loss(TEWL)before,after,and seven days following product use.The four cleansers showed differences in squalene hydroperoxide removal and cholesterol retention,and their selective cleansing ability was quantified using a selective cleansing coefficient.In human tests,the cleanser demonstrated a squalene hydroperoxide removal rate of 97.2%and a change in sebum secretion of-93.26%immediately after cleansing;TEWL changed by-11.77%.After seven days of use,sebum secretion changed by-28.83%,and TEWL changed by-29.77%.These results indicate that the dual-chamber cleanser,which demonstrated selective cleansing on the leather model,achieves selective cleansing in humans while balancing sebum secretion and enhancing the skin barrier.关键词
选择性清洁/角鲨烯过氧化物/胆固醇/皮肤屏障Key words
selective cleansing/squalene hydroperoxide/cholesterol/skin barrier分类
化学化工引用本文复制引用
张文荣,唐莉凤,李雪玩,郭亚玲,周紫燕,叶理..一款具有选择性清洁能力的双管洁面产品的评价方法研究[J].日用化学品科学,2026,49(2):26-33,8.
