山西中医药大学学报2026，Vol.27Issue(1)：28-34,7.DOI:10.19763/j.cnki.2096-7403.2026.01.04
基于国医大师徐经世"杂病论治,重在中州"理论探究绿萼梅对肝"炎-癌转化"的作用机制
Exploration of the mechanism of Lv'emei in liver"inflamation-cancer transformation"based on the theory of"treating miscellaneous diseases by focusing on the middle energizer"by Xu Jingshi
摘要
Abstract
Liver cancer,as a highly prevalent malignant tumor worldwide,poses a serious threat to human health.Its occurrence and development mostly follow the progressive pathological evolution of"hepatitis-cirrhosis-liver cancer".Tra-ditional Chinese Medicine(TCM),with its characteristic advantages of holistic concepts and syndrome differentiation for treatment,holds unique advantages in blocking this malignant transformation chain.Master of TCM Xu Jingshi proposes the academic thought that"the treatment of miscellaneous diseases should focus on the middle energizer",viewing the liver,gallbladder,spleen and stomach as an integrated regulatory center and emphasizing the core role of"regulating the liver and harmonizing the spleen"in preventing and treating internal miscellaneous diseases.Lv'emei,as a traditional Chinese herb,has the effects of soothing the liver to relieve depression,regulating Qi and harmonizing the stomach.Its characteristic of"regulating Qi without damaging Yin"is particularly suitable for the long-term management of liver diseases.By systemati-cally reviewing the academic connotation of Xu Jingshi's"middle energizer theory"and analyzing the TCM pathogenesis characteristics of liver"inflamation-cancer transformation",this study explores the mechanism of Lv'emei in regulating the Qi activity of the middle energizer,improving the state of liver depression and spleen deficiency,and blocking the formation of cancer toxins.It is found that Lv'emei,through its multi-target effects of"soothing the liver and harmonizing the spleen,regulating Qi and resolving phlegm",can effectively intervene in the pathological processes of liver-Qi stagnation and phlegm-stasis intermingling,demonstrating potential value in preventing liver"inflamation-cancer transformation".This provides a new theoretical perspective and practical pathway for TCM in the prevention and treatment of precancerous le-sions of liver cancer,which is of great significance for enriching the theoretical system of TCM in cancer prevention and treatment.关键词
中州理论/绿萼梅/肝"炎-癌转化"/中医药防治/徐经世Key words
middle energizer theory/Lv'emei/liver"inflamation-cancer transformation"/TCM prevention and treat-ment/Xu Jingshi分类
医药卫生引用本文复制引用
李荚若彤,张东伟..基于国医大师徐经世"杂病论治,重在中州"理论探究绿萼梅对肝"炎-癌转化"的作用机制[J].山西中医药大学学报,2026,27(1):28-34,7.基金项目
第七批全国老中医药专家学术经验继承工作(国中医药人教函[2022]76号) （国中医药人教函[2022]76号）
2023年度安徽省卫生健康科研项目(AHWJ2023Bac20189) （AHWJ2023Bac20189）
