陕西师范大学学报（自然科学版）2026，Vol.54Issue(1)：18-26,9.DOI:10.15983/j.cnki.jsnu.2026003
多酚刻蚀ZIF-8对金黄色葡萄球菌的灭菌效果
Studies on the inhibitory effect of polyphenol-etched ZIF-8 on Staphylococcus aureus
摘要
Abstract
The limited visible light absorption and relatively large bandgap of zeolitic imidazolate framework-8(ZIF-8)substantially restrict its antibacterial efficacy under visible light irradiation.Herein,a novel visible-light-responsive antibacterial nanocomposite,EGCG@ZIF-8,was synthesized via post-synthetic modification through the etching of ZIF-8 with epigallocatechin gallate(EGCG).Under visible light irradiation,EGCG@ZIF-8 can efficiently generate reactive oxygen species(ROS),demonstrating a antibacterial rate of 99.999 9％against Staphylococcus aureus within 60 min,which significantly surpassed the performance of pristine ZIF-8.Furthermore,EGCG@ZIF-8 retained robust antibacterial activity even after five consecutive usage cycles.The incorporation of EGCG narrowed the bandgap of ZIF-8,promoting the separation and migration of photogenerated electron-hole pairs,which enhanced the visible-light photocatalytic performance of the composite and subsequently boosted ROS generation.In addition,in vitro cytotoxicity assays confirmed the outstanding biocompatibility of EGCG@ZIF-8.This study not only offers a straightforward and efficient approach for synthesizing high-performance antibacterial composites,but also paves the way for the development of innovative visible-light-driven antibacterial materials,underscoring its substantial scientific and practical significance.关键词
EGCG@ZIF-8/ROS/金黄色葡萄球菌/可见光催化/抗菌活性Key words
EGCG@ZIF-8/ROS/Staphylococcus aureus/visible-light photocatalysis/antibacterial activity分类
轻工纺织引用本文复制引用
陈梦秋,刘雁玲,马臣辰,金敏,李海北,侯丽华..多酚刻蚀ZIF-8对金黄色葡萄球菌的灭菌效果[J].陕西师范大学学报（自然科学版）,2026,54(1):18-26,9.基金项目
国家重点研发计划(2022YFC2604004) （2022YFC2604004）
