现代妇产科进展2026，Vol.35Issue(1)：1-8,8.DOI:10.13283/j.cnki.xdfckjz.2026.01.001
子宫颈上皮内瘤变2级(CIN2)管理中国专家共识(2026版)
Chinese expert consensus on the management of cervical intraepithelial neoplasia grade 2(CIN2)(2026 edition)
摘要
Abstract
Persistent infection with high-risk human papillomavirus(HR-HPV)is the primary etiologi-cal factor for cervical intraepithelial neoplasia grade 2(CIN2).The accuracy of CIN2 diagnosis is affected by the limitations of colposcopic biopsy and the variability in pathological interpretation.Underdiagnosis or overdiagno-sis may lead to missed detection of more severe lesions or overtreatment.Particularly for young women and those with fertility requirement,overtreatment can increase the risk of adverse pregnancy outcomes in the future.Based on evidence-based medicine and China's national conditions,this consensus proposes refined management strate-gies for the CIN2 women.Comprehensive consideration of multiple factors(including age,fertility needs,and le-sion characteristics,etc)is required,for low-risk individuals eligible for conservative observation,close monito-ring and dynamic assessment should be implemented.For high-risk individuals ineligible for conservative obser-vation,it is recommended to undergo excisional treatment to reduce the risk of missed diagnosis and disease pro-gression.For special populations of CIN2:follow-up is the mainstay for pregnant women,with reassessment post-delivery;excisional treatment is preferred for postmenopausal women;and immunocompromised women require individualized assessment,enhanced monitoring,or active treatment.关键词
子宫颈上皮内瘤变2级/保守观察/治疗/随访Key words
Cervical intraepithelial neoplasia grade 2/Conservative observation/Treatment/Follow-up分类
医药卫生引用本文复制引用
中国优生科学协会阴道镜和宫颈病理学分会,中华医学会妇科肿瘤学分会,隋龙,孔北华,马丁,魏丽惠..子宫颈上皮内瘤变2级(CIN2)管理中国专家共识(2026版)[J].现代妇产科进展,2026,35(1):1-8,8.基金项目
国家重点研发项目(No:2025YFC2708404) （No:2025YFC2708404）
