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EBV阳性弥漫大B细胞淋巴瘤合并细胞因子释放综合征的诊治

孔琦 马骥 郭志军

协和医学杂志2026,Vol.17Issue(1):33-39,7.
协和医学杂志2026,Vol.17Issue(1):33-39,7.DOI:10.12290/xhyxzz.2025-0815

EBV阳性弥漫大B细胞淋巴瘤合并细胞因子释放综合征的诊治

Diagnosis and Treatment of Epstein-Barr Virus-Positive Diffuse Large B-cell Lymphoma Complicated by Cytokine Release Syndrome

孔琦 1马骥 1郭志军2

作者信息

  • 1. 山东第一医科大学附属肿瘤医院 淋巴血液科,济南 250117
  • 2. 山东第一医科大学附属肿瘤医院 重症监护室,济南 250117
  • 折叠

摘要

Abstract

Epstein-Barr virus-positive diffuse large B-cell lymphoma,not otherwise specified(EBV+DLBCL,NOS)is a lymphoma subtype characterized by distinct biological features and a poor prognosis.This disease is frequently complicated by cytokine release syndrome(CRS),a severe condition closely linked to its intrinsic biological characteristics,which is receiving increasing clinical attention.This article systematically elaborates on the latest advances in the molecular mechanisms,diagnostic grading,and therapeutic strategies for EBV+DLBCL,NOS complicated by CRS,aiming to provide a more comprehensive evidence-based founda-tion for clinical decision-making.

关键词

Epstein-Barr病毒/弥漫大B细胞淋巴瘤/细胞因子释放综合征/噬血细胞性淋巴组织细胞增多症

Key words

Epstein-Barr virus/diffuse large B-cell lymphoma/cytokine release syndrome/hemophagocytic lympho-histiocytosis

分类

医药卫生

引用本文复制引用

孔琦,马骥,郭志军..EBV阳性弥漫大B细胞淋巴瘤合并细胞因子释放综合征的诊治[J].协和医学杂志,2026,17(1):33-39,7.

基金项目

Noncommunicable Chronic Diseases-National Science and Technology Major Project(2024ZD0526104) 四大慢病重大专项(2024ZD0526104) (2024ZD0526104)

协和医学杂志

1674-9081

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