协和医学杂志2026,Vol.17Issue(1):33-39,7.DOI:10.12290/xhyxzz.2025-0815
EBV阳性弥漫大B细胞淋巴瘤合并细胞因子释放综合征的诊治
Diagnosis and Treatment of Epstein-Barr Virus-Positive Diffuse Large B-cell Lymphoma Complicated by Cytokine Release Syndrome
摘要
Abstract
Epstein-Barr virus-positive diffuse large B-cell lymphoma,not otherwise specified(EBV+DLBCL,NOS)is a lymphoma subtype characterized by distinct biological features and a poor prognosis.This disease is frequently complicated by cytokine release syndrome(CRS),a severe condition closely linked to its intrinsic biological characteristics,which is receiving increasing clinical attention.This article systematically elaborates on the latest advances in the molecular mechanisms,diagnostic grading,and therapeutic strategies for EBV+DLBCL,NOS complicated by CRS,aiming to provide a more comprehensive evidence-based founda-tion for clinical decision-making.关键词
Epstein-Barr病毒/弥漫大B细胞淋巴瘤/细胞因子释放综合征/噬血细胞性淋巴组织细胞增多症Key words
Epstein-Barr virus/diffuse large B-cell lymphoma/cytokine release syndrome/hemophagocytic lympho-histiocytosis分类
医药卫生引用本文复制引用
孔琦,马骥,郭志军..EBV阳性弥漫大B细胞淋巴瘤合并细胞因子释放综合征的诊治[J].协和医学杂志,2026,17(1):33-39,7.基金项目
Noncommunicable Chronic Diseases-National Science and Technology Major Project(2024ZD0526104) 四大慢病重大专项(2024ZD0526104) (2024ZD0526104)