畜牧兽医学报2026,Vol.57Issue(1):1-12,12.DOI:10.11843/j.issn.0366-6964.2026.01.001
家畜单细胞转录组学数据库的研究现状与展望
Research Status and Prospects of Livestock Single-cell Transcriptomics Databases
摘要
Abstract
This article aims to elucidate how single-cell omics technologies advance livestock research and provides a systematic review of the construction process,current applications,and major challenges of single-cell transcriptomic databases in domestic animals.It seeks to offer data references and analytical frameworks for researchers,thereby promoting deeper application of this technology in livestock studies.This review conducted a comprehensive review and integrated analysis of existing single-cell transcriptomic database resources for livestock,summarizing their construction methodologies and application pathways,while also discussing current technical bottlenecks.The review demonstrates that single-cell transcriptomics offers novel perspectives and abundant data resources for elucidating mechanisms of livestock diseases,molecular breeding,and health management,while also revealing significant challenges in areas such as data integration and annotation standardization.Future efforts should focus on constructing high-quality databases,developing analysis algorithms tailored to livestock species,and promoting multi-omics integration to fully leverage the potential of single-cell technologies in the development of animal husbandry.关键词
家畜/单细胞转录组学/数据库Key words
livestock/single-cell transcriptomics/database分类
农业科技引用本文复制引用
王健,李瑞星,刘翘铭,李远方..家畜单细胞转录组学数据库的研究现状与展望[J].畜牧兽医学报,2026,57(1):1-12,12.基金项目
河南省科技攻关项目(221100110200) (221100110200)
国家自然科学基金(62402145) (62402145)