畜牧兽医学报2026，Vol.57Issue(1)：80-95,16.DOI:10.11843/j.issn.0366-6964.2026.01.008
m6A修饰调控miRNAs影响细胞能量代谢的研究进展
Research Progress on m6A Modification Regulation of miRNAs Affecting Cellular Energy Metabolism
摘要
Abstract
N6-methyladenosine(m6A)modification and microRNAs(miRNAs)are important factors in gene expression regulation,playing a crucial role in cellular energy metabolism.m6A modification participates in various physiological and pathological processes by regulating RNA stability,splicing and translation.miRNAs,as a class of small molecule RNAs,directly affect cellular metabolic pathways by targeting and regulating gene expression.The m6A modification-mediated regulation of miRNAs plays a pivotal role in cellular energy metabolism,especially in regulating metabolic processes such as glycolysis and mitochondrial function.By discussing the regulatory effect of m6A modification on miRNAs and its impact on energy metabolism,this review elaborating in detail on the mechanism by which m6A modification affects cellular energy metabolism by regulating miRNAs,and reveals the possibility of m6A modified miRNAs as targets for regulating cellular energy metabolism,in order to provide a theoretical reference for regulating animal growth and development and treating energy metabolism-related diseases.关键词
m6A修饰/miRNAs/能量代谢/线粒体Key words
m6A modification/miRNAs/energy metabolism/mitochondria分类
农业科技引用本文复制引用
邓雯心,李怡涵,王倩,朱娆希,李函亭,张姣姣..m6A修饰调控miRNAs影响细胞能量代谢的研究进展[J].畜牧兽医学报,2026,57(1):80-95,16.基金项目
国家自然科学基金面上项目(32273071) （32273071）
重庆市自然科学基金面上项目(CSTB2024NSCQ-MSX0231) （CSTB2024NSCQ-MSX0231）
中央高校基本科研业务费专项资金(SWU-XDJH202307) （SWU-XDJH202307）
西南大学大学生创新创业训练计划项目(X202410635706) （X202410635706）
