临床研究2026，Vol.34Issue(2)：9-12,4.DOI:10.12385/j.issn.2096-1278(2026)02-0009-04
磁共振成像征象与子宫内膜癌患者脉管间隙浸润的相关性分析
Correlation Between Magnetic Resonance Imaging Findings and Lymphovascular Space Invasion in Patients with Endometrial Cancer
叶子涵 1刘士连1
作者信息
- 1. 南阳医学高等专科学校第一附属医院 妇科,河南 南阳 467000
- 折叠
摘要
Abstract
Objective To investigate the association between quantitative magnetic resonance imaging(MRI)parameters and lymphovascular space invasion(LVSI)in patients with endometrial cancer.and to provide imaging-based evidence for surgical decision-making and individualized treatment.Methods A retrospective analysis was performed on 90 patients with endometrial cancer who were admitted to the Department of Gynecology.The First Affiliated Hospital of Nanyang Medical College.between June 2023 and June 2025 and were pathologically confirmed.According to postoperative pathological findings.patients were divided into an LVSI-positive group(n=45)and an LVSI-negative group(n=45).All patients underwent preoperative pelvic MRI.and MRI-related variables were collected.Differences in baseline characteristics and MRI parameters between the two groups were analyzed.Collinearity among variables showing between-group differences was assessed using variance inflation factor.tolerance.and Pearson/Spearman correlation analyses.Multivariable logistic regression analysis was then conducted to identify factors associated with LVSI in patients with endometrial cancer.Results Compared with the LVSI-negative group.the LVSI-positive group had significantly greater maximum tumor diameter and tumor volume.and significantly higher values of Ktrans.Kep.and Ve(P＜0.05).while the apparent diffusion coefficient(ADC)was significantly lower(P＜0.05).In addition.the LVSI-positive group had a higher proportion of lymph node enlargement(P＜0.05).After collinearity assessment.tumor volume was excluded.and the remaining variables were entered into the multivariable logistic regression model.The results showed that an increased maximum tumor diameter(OR=2.085.P=0.002)and elevated Ktrans(OR=2.303.P=0.030)were independent risk factors for LVSI.whereas a higher ADC value(OR=0.742.P=0.007)was an independent protective factor.Conclusion Multiparametric MRI is of significant value for preoperative evaluation of endometrial cancer.An increased maximum tumor diameter.decreased ADC.and elevated Ktrans may be closely associated with the presence of LVSI in patients with endometrial cancer.关键词
子宫内膜癌/脉管间隙浸润/磁共振成像/相关性分析Key words
endometrial cancer/lymphovascular space invasion/magnetic resonance imaging/correlation analysis分类
医药卫生引用本文复制引用
叶子涵,刘士连..磁共振成像征象与子宫内膜癌患者脉管间隙浸润的相关性分析[J].临床研究,2026,34(2):9-12,4.
