肿瘤防治研究2026,Vol.53Issue(1):17-20,4.DOI:10.3971/j.issn.1000-8578.2026.25.0725
多发性骨髓瘤分层诊断的现状和展望
Current Status and Prospects of Stratified Diagnosis of Multiple Myeloma
侯健 1方施1
作者信息
- 1. 200127 上海,上海交通大学医学院附属仁济医院血液科
- 折叠
摘要
Abstract
Multiple myeloma(MM)is an incurable and malignant plasma cell tumor that has been shown to have significant variations in treatment responses and survival outcomes among patients.In recent years,advances in genomics,molecular biology,and immunology have greatly improved the ability to identify patients at different risk levels,thus laying the foundation for personalized treatment.As clinical and molecular markers continue to integrate,the risk stratification system for MM has evolved.However,current systems continue to face challenges in accurately identifying key molecular events,the impact of the bone marrow microenvironment,and tumor clonal evolution.In the context of novel immunotherapies and targeted therapies,advanced technologies are providing critical tools for developing more refined and multidi-mensional risk models.Therefore,conducting in-depth exploration and refinement of new stratified diagnostic systems is essential for improving the prognosis of MM patients and advancing precision diagnosis and treatment.关键词
多发性骨髓瘤/风险分层/精准医学Key words
Multiple myeloma/Stratified diagnosis/Precision medicine分类
医药卫生引用本文复制引用
侯健,方施..多发性骨髓瘤分层诊断的现状和展望[J].肿瘤防治研究,2026,53(1):17-20,4.