安徽农学通报2026，Vol.32Issue(4)：89-94,6.DOI:10.16377/j.cnki.issn1007-7731.2026.04.021
基于非靶向代谢组学的卷烟制品代谢物差异分析
Differential analysis of metabolite components in cigarette products based on untargeted metabolomes
摘要
Abstract
To investigate the differences in metabolic components of cigarettes,type Ⅰcigarettes(100HHL96,100HTXC,100HTXX,100TY,100ZH)and type Ⅱ cigarettes(10DQM,10HJY,10XSD,35FRW,35HEH)were used as materials.Gas chromatography-mass spectrometry(GC-MS)and liquid chromatography-mass spectrometry(LC-MS)were employed to analyze the metabolic components of the two types of cigarette products,and metabolomic methods were used for heterogeneity analysis.The results showed that a total of 785 metabolic substances were identified across the 10 cigarette samples,with ketones(15%),esters and lipid molecules(10%),and terpenes(10%)ranking in the top three categories by structure,and ketones,alkaloids,and indoles ranking in the top three categories by content.In the comparison of two types of cigarette products,28 metabolites such as dimethyldodecylamine and L-pyroglutamic acid,and dihydrocelastryl diacetate showed significant differentiation.In type Ⅰ cigarettes,11 metabolites such as dimethyldodecylamine,L-pyroglutamic acid,and 5-hydroxymaltol were upregulated,while 17 metabolites such as dihydroquercetin diacetate,ethyl palmitate,and ethyl octadecanoate were downregulated.The main components affecting aroma,such as mesmin,methyl palmitate,and maltol,showed significant heterogeneity between the two types of cigarettes.This study provides a reference for improving cigarette processing technology and product quality.关键词
卷烟/气相色谱-质谱联用/液相色谱-质谱联用/异质性Key words
cigarette/gas chromatography-mass spectrometry/liquid chromatography-mass spectrometry/heterogeneity分类
农业科技引用本文复制引用
陈泽鹏,陈东豪,刘桔,陈雨峰,栾新博,彭依怡,黎平,颜健..基于非靶向代谢组学的卷烟制品代谢物差异分析[J].安徽农学通报,2026,32(4):89-94,6.基金项目
广东省烟草专卖局(公司)项目"广东焦甜醇甜香型标志性烟叶风格特色研究及应用开发"(2023440000240043). （公司）
