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重庆市高疫情地区病原学阴性肺结核的诊断质量现状

余雅 苏倩 陈健 雷蓉蓉 唐杰 吴成果 范君 郑登虎

重庆医学2026,Vol.55Issue(1):82-85,92,5.
重庆医学2026,Vol.55Issue(1):82-85,92,5.DOI:10.3969/j.issn.1671-8348.2026.01.014

重庆市高疫情地区病原学阴性肺结核的诊断质量现状

Diagnostic quality status quo of etiological negative pulmonary tuberculosis in high epidemic areas of Chongqing City

余雅 1苏倩 2陈健 1雷蓉蓉 1唐杰 1吴成果 3范君 3郑登虎3

作者信息

  • 1. 重庆市结核病防治所:区县科,重庆 400050
  • 2. 重庆市结核病防治所:综合防治科,重庆 400050
  • 3. 重庆市结核病防治所:行政办公室,重庆 400050
  • 折叠

摘要

Abstract

Objective To analyze the status quo of diagnostic quality of pulmonary tuberculosis(PTB)with etiological negative in some high epidemic areas in Chongqing City to provide the scientific evidence for optimizing related diagnostic strategies.Methods The patients with pathogenic negative PTB who were regis-tered and treated in the designated medical institutions in six districts and counties in the southeastern and northeastern areas of Chongqing where the epidemic situation was relatively severe in 2023 were selected as the research subjects.The case data of the patients were collected.The municipal expert group conducted the on-site review and evaluated the quality of the original diagnosis.Results Among 463 cases of etiological neg-ative,2.3%of the cases did not undergo the sputum smear examination,while the patients undergoing the sputum culture and molecular biological test accounted for 60.0%and 88.1%respectively.60.5%of the pa-tients conducted the anti-tuberculosis antibody test,and the patients conducting the tuberculin skin tests(26.6%)and interferon-γ release assay(35.6%)did not excess 40.0%.All patients conducted the chest X-ray and DR examination,and 226 cases simultaneously conducted the CT examination.Among them,the chest imageologic results in 368 patients were basically accordant with the primary interpretation in the local fixed-point hospitals.Sixteen patients conducted the normative anti-infection treatment.Forty-four patients execu-ted the discussion of the diagnosis group according to the norms before diagnosis.The overall diagnostic coin-cidence rate was 90.1%(417/463),the over-diagnosis rate was 6.7%(31/463),and the missed diagnosis rate was 3.2%(15/463).Conclusion The PTB diagnostic coincidence rate of etiological negative PTB patients in the high epidemic areas in Chongqing City was 90.1%.The related TB designated medical institutions need to increase the capabilities of identifying active PTB and other lung diseases.

关键词

高疫情地区/肺结核/诊断/病原学阴性/现状

Key words

high-epidemic areas/pulmonary tuberculosis/diagnostic/pathogenic negative/status quo

分类

医药卫生

引用本文复制引用

余雅,苏倩,陈健,雷蓉蓉,唐杰,吴成果,范君,郑登虎..重庆市高疫情地区病原学阴性肺结核的诊断质量现状[J].重庆医学,2026,55(1):82-85,92,5.

基金项目

重庆市公共卫生重点专(学)科建设项目 (学)

重庆市中青年医学高端人才项目(YXGD202439) (YXGD202439)

重庆市科卫联合医学科研项目(2023MSXM143) (2023MSXM143)

重庆市卫生健康委医学科研项目(2025WSJK107). (2025WSJK107)

重庆医学

1671-8348

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