湖南中医杂志2026，Vol.42Issue(1)：38-42,5.DOI:10.16808/j.cnki.issn1003-7705.2026.01.009
基于"脾脑同治"理论应用针刺联合自拟定痫宁治疗癫痫风痰闭窍证35例
Clinical effect of acupuncture combined with self-made Dingxianning in treatment of epilepsy with syndrome of wind-phlegm blocking orifices based on the theory of"simultaneous treatment of spleen and brain":An analysis of 35 cases
摘要
Abstract
0bjective:To investigate the clinical effect of acupuncture combined with self-made Dingxianning in the treatment of epilepsy with syndrome of wind-phlegm blocking orifices based on the theory of"simultaneous treatment of spleen and brain".Methods:A total of 70 patients with epilepsy with syndrome of wind-phlegm blocking orifices were randomly divided into treatment group and control group,with 35 patients in each group.The patients in the control group were given standardized antiepileptic medication,while those in the treatment group were given acupuncture combined with self-made Dingxianning in addition to the treatment in the control group,and the course of treatment was 90 days for both groups.The two groups were compared in terms of traditional Chinese medicine(TCM)syndrome score,seizure frequency,the serum levels of inflammatory factors,electroencephalogra-phy improvement,routine blood test results,liver and renal function,and adverse reactions before and after treatment,and clinical outcome was assessed.Results:There was a significant difference in overall response rate between the treatment group and the control group[94.29％(33/35)vs 85.71％(30/35),P＜0.05],and there was also a significant difference in electroencephalography improvement between the two groups[97.14％(34/35)vs 82.86％(29/35),P＜0.05].Both groups had significant changes in TCM syndrome score,seizure frequency,and the serum levels of inflammatory factors after treatment,and there were significant differences in these indicators between the two groups after treatment(P＜0.05).There were no significant differences in routine blood test results,liver and renal function,and adverse reactions between the two groups(P＞0.05).Conclusion:Based on the theory of"simultaneous treatment of spleen and brain",acupuncture combined with self-made Dingxianning can improve the clinical symptoms of patients with epilepsy with syndrome of wind-phlegm blocking orifices,reduce the serum levels of inflammatory factors,improve electroencephalography findings,and enhance quality of life,and it is safe and effective without obvious adverse reactions.关键词
癫痫/风痰闭窍证/"脾脑同治"理论/针刺/中药/自拟定痫宁Key words
epilepsy/syndrome of wind-phlegm blocking orifices/theory of"simultaneous treatment of spleen and brain"/acupuncture/traditional Chinese medicine/self-made Dingxianning分类
医药卫生引用本文复制引用
张秀胜,孙玄静..基于"脾脑同治"理论应用针刺联合自拟定痫宁治疗癫痫风痰闭窍证35例[J].湖南中医杂志,2026,42(1):38-42,5.基金项目
江苏省徐州市卫生健康委员会项目(XWKYHT20240052) （XWKYHT20240052）
