儿科药学杂志2026，Vol.32Issue(2)：25-28,4.DOI:10.13407/j.cnki.jpp.1672-108X.2026.02.006
多维铁联合右旋糖酐铁口服液治疗儿童缺铁性贫血的临床评价
Efficacy of Multi-Dimensional Iron Combined with Iron Dextran Oral Solution in the Treatment of Children with Iron Deficiency Anemia and Its Effects on Serum Ferritin
摘要
Abstract
Objective:To probe into the efficacy of multi-dimensional iron combined with iron dextran oral solution in the treatment of children with iron deficiency anemia(IDA)and its effects on serum ferritin(SF).Methods:Ninety-six children with IDA admitted into Cangzhou Central Hospital from Sept.2023 to Sept.2024 were extracted,5 cases dropped out due to personal reasons,and 91 cases were finally enrolled.The children were divided into the iron dextran group(iron dextran oral solution,45 cases)and combined group(multi-dimensional iron oral solution combined with iron dextran oral solution,46 cases)via the random number table method.The clinical efficacy,anemia related indicators,iron metabolism related indicators,serum indicators,and adverse drug reactions of two groups were compared.Results:After treatment,the total effective rate of combined group was higher than that of iron dextran group(P＜0.05).The red blood cell count(RBC),hemoglobin(Hb),mean corpuscular hemoglobin concentration(MCHC),and mean corpuscular volume(MCV)in both groups increased significantly,and the combined group was higher than the dextran iron group(P＜0.05).After treatment,the serum iron(SI)and SF in both groups increased,and the combined group was higher than the dextran iron group(P＜0.05).The total iron binding capacity(TIBC)of both groups decreased,and the combined group was lower than the dextran iron group(P＜0.05).After treatment,the levels of interleukin-6(IL-6)and interferon-γ(INF-γ)in both groups decreased,and the combined group was lower than the dextran iron group(P＜0.05).The level of IL-10 in both groups increased,and the combined group was higher than the dextran iron group(P＜0.05).Conclusion:Multi-dimensional iron combined with iron dextran oral solution in the treatment of children with IDA can effectively supplement the iron elements,improve the anemia symptoms with higher safety.关键词
缺铁性贫血/多维铁/右旋糖酐铁口服液/血清铁蛋白Key words
iron deficiency anemia/multi-dimensional iron/iron dextran oral solution/serum ferritin分类
医药卫生引用本文复制引用
李琛,刘朝阳,王文娟,齐莹莹..多维铁联合右旋糖酐铁口服液治疗儿童缺铁性贫血的临床评价[J].儿科药学杂志,2026,32(2):25-28,4.基金项目
河北省2024年度医学科学研究课题计划项目,编号20241742. （）
