发育医学电子杂志2026，Vol.14Issue(1)：65-73,9.DOI:10.3969/j.issn.2095-5340.2026.01.010
营养素肌醇在胚胎神经发育中的作用及动态进展
Role and dynamic progress of the nutrient inositol in embryonic neural development
摘要
Abstract
Embryonic neural development originates from the ectoderm,which first differentiates into the neural plate.It folds inward along the midline to form the neural groove.The lateral edges of the groove gradually elevate to form neural folds,which converge and fuse at the dorsal midline to form the neural tube.The neural tube,as the precursor of the central nervous system,plays an important role in the process of embryonic neural development.Inositol,a nutrient classified as a cyclitol,is a derivative of cyclohexanone.It mainly exists in free form as phosphatidylinositol,or as inositol phosphate derivatives within the body.And it is involved in various physiological processes of neural cells and plays key roles in signal transduction,gene expression regulation,and other cellular activities.This article reviews the role and dynamic progress concerning inositol in embryonic neural development,aiming to provide new insights for the early intervention,diagnosis,and treatment of neurodevelopmental disorders,as well as to further elucidate the role and mechanisms of inositol influences neural development.关键词
肌醇/代谢/神经管畸形/发育/干预Key words
Inositol/Metabolism/Neural tube defect/Development/Prevention引用本文复制引用
高行健,韦明仙,王建华..营养素肌醇在胚胎神经发育中的作用及动态进展[J].发育医学电子杂志,2026,14(1):65-73,9.基金项目
国家自然科学基金(U23A20420) （U23A20420）
北京市自然科学基金(7244290.7222016.7244291) （7244290.7222016.7244291）
