口腔疾病防治2026，Vol.34Issue(2)：139-147,9.DOI:10.12016/j.issn.2096-1456.202550442
5T MRI对青年人群牙髓及牙周膜的体内成像效果研究
Study on the in vivo effects of 5T magnetic resonance imaging on the dental pulp and periodontal ligament in young adults
摘要
Abstract
Objective To evaluate the performance of 5T magnetic resonance imaging(MRI)in visualizing dental pulp and periodontal ligament(PDL)tissues in vivo in the young adult population,thereby providing a basis for the ap-plication of high-field MRI technology in clinical oral examinations.Methods The study was approved by the Ethics Committee of the hospital.A total of 15 healthy volunteers(413 permanent teeth altogether)were recruited and under-went full-mouth 5T MRI scans.Among them,six volunteers(168 permanent teeth)also received both 3T MRI and cone-beam computed tomography(CBCT)scans.Two dental specialists independently evaluated the imaging quality of the dental pulp and PDL on the images using a 5-point Likert scale and recorded the number of detectable root canals for each tooth.Inter-rater agreement was assessed using weighted kappa statistics and intraclass correlation coefficient(ICC).Non-parametric tests were employed to compare differences in imaging performance among different tissue struc-tures,tooth positions,and imaging modalities.Results 5T MRI can achieve in vivo imaging for most dental pulp tis-sues and partial periodontal membrane structures.There was a high level of agreement between the two raters in their imaging scores for the dental pulp and PDL(dental pulp κ=0.934,PDL κ=0.737).The imaging scores for dental pulp were significantly higher than those for PDL(P<0.001),and the scores for molar dental pulp were lower than those for premolars and anterior teeth.In the multimodal comparison involving six volunteers,the raters showed good consistency in scoring dental pulp and PDL imaging across 5T MRI,3T MRI,and CBCT,as well as in root canal counts(5T MRI for dental pulp κ=0.971,3T MRI for dental pulp κ=0.933,CBCT for dental pulp κ=0.964;5T MRI for PDL κ=0.625,3T MRI for PDL κ=0.667,CBCT for PDL κ=0.571;ICC for root canal counts all≥0.990).The imaging scores for dental pulp and PDL using 5T MRI were significantly higher than those using 3T MRI(dental pulp:P<0.001;PDL:P=0.022),but there was no statistically significant difference in the detection rate of the number of root canals between the two(P>0.05).Although the imaging scores for dental pulp and PDL as well as the detection rate of the number of root canals with 5T MRI were inferior to those with CBCT(dental pulp:P<0.001;PDL:P=0.02;number of root canals:P<0.05),5T MRI can truly achieve"direct imaging"of these two soft tissues.Conclusion 5T MRI en-ables effective in vivo direct imaging of dental pulp and PDL tissues in the young adult population,indicating its poten-tial clinical application value in the diagnosis and treatment of pulp and periodontal diseases.关键词
5T磁共振成像/3T磁共振成像/锥形束CT/牙髓/牙周膜/体内成像/软组织对比/直接成像Key words
5T magnetic resonance imaging/3T magnetic resonance imaging/cone-beam computed tomogra-phy/dental pulp/periodontal ligament/in vivo imaging/soft tissue contrast/direct imaging分类
医药卫生引用本文复制引用
漆正楠,曹轶婷,王易维,宋庆博,张培荣,孙顺涛,汪登斌,唐子圣..5T MRI对青年人群牙髓及牙周膜的体内成像效果研究[J].口腔疾病防治,2026,34(2):139-147,9.基金项目
国家重点研发计划(2022YFC2402105) （2022YFC2402105）
上海交通大学医学院附属新华医院"学科攀峰计划"项目(XKPF2024B50021,XKPF2024B50024) This study was supported by the grants from the National Key Research and Development Program of China(No.2022YFC2402105) （XKPF2024B50021,XKPF2024B50024）
the Construction Project of the"Discipline Peak-Climbing Plan"of Xinhua Hospital,Shanghai Jiao Tong University School of Medicine(No.XKPF2024B50021,No.XKPF2024B50024). （No.XKPF2024B50021,No.XKPF2024B50024）
