广州中医药大学学报2026，Vol.43Issue(2)：433-438,6.DOI:10.13359/j.cnki.gzxbtcm.2026.02.022
基于"脾主运化"探讨针灸治疗慢性疲劳综合征的"肠道菌群-线粒体"轴调控机制
Exploring the Regulatory Mechanism of the"Gut Microbiota-Mitochondria"Axis in Acupuncture Treatment for Chronic Fatigue Syndrome Based on the Theory of"Spleen Governing Transportation and Transformation"
摘要
Abstract
Chronic fatigue syndrome(CFS)is a complex disease characterized by persistent fatigue as the core symptom.The traditional Chinese medicine theory of"Spleen Governing Transportation and Transformation"provides a unique perspective for its treatment.This study establishes a theoretical model of"Spleen Governing Transportation and Transformation-Microbiota Homeostasis-Mitochondrial Energy Metabolism",proposing that acupuncture improves CFS through regulation of the"gut microbiota-mitochondria"axis,and analyzes the advantages and efficacy differences of acupuncture treatment.Results demonstrate that acupuncture can restore gut microbiota homeostasis,inhibit mitochondrial oxidative stress,and enhance mitochondrial ATP synthesis capacity,providing a new theoretical basis for acupuncture treatment of CFS.关键词
针灸治疗/脾主运化/慢性疲劳综合征/肠道菌群/线粒体能量代谢/调控机制Key words
acupuncture treatment/spleen governing transportation and transformation/chronic fatigue syndrome(CFS)/gut microbiota/mitochondrial energy metabolism/regulatory mechanism分类
医药卫生引用本文复制引用
王中豪,刘婷,廖穆熙..基于"脾主运化"探讨针灸治疗慢性疲劳综合征的"肠道菌群-线粒体"轴调控机制[J].广州中医药大学学报,2026,43(2):433-438,6.基金项目
广东省基础与应用基础研究基金自然科学基金面上项目(编号:2023A1515011411) （编号:2023A1515011411）
广东省科技厅农村科技(特派员)项目(编号:KTPYJ2021026) （特派员）
深圳市南山区高层次医学团队引进项目(编号:SZSM202103010) （编号:SZSM202103010）
广州中医药大学"双一流"与高水平大学学科高质量发展"筑峰造尖"行动计划"固本工程"项目(编号:GZY2025GB0204) （编号:GZY2025GB0204）
