四川大学学报(医学版)2026,Vol.57Issue(1):291-298,8.DOI:10.12182/20260160201
脂肪组织与多器官交互调控的研究进展
Recent Advances in the Interorgan Regulatory Roles of Adipose Tissue
摘要
Abstract
Adipose tissue,a vital component of the human body,serves multiple functions,including energy storage,thermal insulation,and protection.Fat is a highly active,dynamic organ that communicates with other organs,playing a crucial role in maintaining health and is closely linked to the onset and progression of diseases.Chronic diseases associated with adipose tissue result from dysregulated inter-organ interactions and have become a major public health challenge.A systematic review of regulatory networks centered on adipose tissue could help overcome the limitations of single-organ studies and identify key inter-organ communication pathways.This article reviews recent advances regarding adipose tissue as a pivotal signaling hub that facilitates inter-organ communication with the liver,gut,brain,and bone,as well as its connection to tumor progression.The review also highlights the applications of cutting-edge technologies such as single-cell sequencing and artificial intelligence in adipose tissue research.Continued exploration of the crosstalk between adipose tissue and other organs holds great potential for disease treatment and health management.关键词
脂肪组织/器官交互调控/健康管理/综述Key words
Adipose tissue/Organ crosstalk/Health management/Review引用本文复制引用
黎祖岑,徐淳义,徐若诗,周陈晨,樊怡..脂肪组织与多器官交互调控的研究进展[J].四川大学学报(医学版),2026,57(1):291-298,8.基金项目
This work was supported by the National Natural Science Foundation of China(No.82370945). 国家自然科学基金(No.82370945)资助 (No.82370945)