结核与肺部疾病杂志2026，Vol.7Issue(1)：92-100,9.DOI:10.19983/j.issn.2096-8493.20250131
进阶式呼吸康复训练在中青年结核后肺疾病患者中的应用效果分析
Efficacy of progressive respiratory rehabilitation training in middle-aged and young patients with post-tuberculosis lung disease
摘要
Abstract
Objective:To investigate the effects of progressive respiratory rehabilitation training on pulmonary function,exercise endurance,and quality of life in middle-aged and young patients with post-tuberculosis lung disease(PTLD).Methods:In this prospective study,77 middle-aged and young PTLD patients admitted to the Department of the Third Pulmonary Disease,Shenzhen Third People's Hospital between September 2022 and June 2024 were enrolled according to inclusion criteria.Eligible patients were randomly assigned,using a random number table,to either a control group(n=38;receiving conventional specialized nursing and respiratory rehabilitation exercises)or a observation group(n=39;receiving progressive intensive respiratory rehabilitation training in addition to the control regimen).Both groups received individualized case management for 6 months.Pulmonary function indices(FEV1％,FVC％),exercise endurance(6-minute walk distance(6MWD)),grip strength,and quality of life(SF-36 scores)were assessed before the intervention,and at 1 and 6 months post-intervention.Results:At one month after the intervention,the observation group's 6MWD was significantly lower than that of the control group((461.77±84.49)m vs.(506.47±78.43)m;t=2.405,P=0.019).However,by six months,the 6MWD in the observation group was significantly higher than in the control group((580.05±78.68)m vs.(532.61±88.18)m;t=2.493,P=0.015).Similarly,at six months,the observation group demonstrated significantly greater improvements in grip strength((32.13±6.05)kg vs.(28.76±8.10)kg;t=2.072,P=0.042),FEV1％((74.77±12.76)％vs.(66.76±19.31)％;t=2.140,P=0.036),and FVC％((86.97±14.17)％vs.(79.01±16.61)％;t=2.268,P=0.026)than the control group.In addition,the mental health scores of the observation group improved to(72.03±13.32)points one month after the intervention,while the overall quality of life scores increased to(636.66±82.28)points at six months.Both scores were significantly higher than those of the control group(65.39±13.40)and(562.64±83.07)points,respectively,with statistically significant differences(t=2.178,P=0.033;t=3.928,P＜0.001).Conclusion:Progressive respiratory rehabilitation training markedly enhances exercise endurance,improves pulmonary function,and elevates the quality of life in middle-aged and young patients with post-tuberculosis lung disease.These findings support the broader clinical application in the management of PTLD.关键词
结核,肺/预后/肺疾病/中年/康复护理/呼吸锻炼Key words
Tuberculosis,pulmonary/Prognosis/Lung diseases/Middle aged/Rehabilitation nursing/Breathing exercises分类
医药卫生引用本文复制引用
王秀芬,罗莉,宋美娟,余翠英,刘欢,魏冉,张丹丹,李剑..进阶式呼吸康复训练在中青年结核后肺疾病患者中的应用效果分析[J].结核与肺部疾病杂志,2026,7(1):92-100,9.基金项目
深圳市高水平医院专项建设项目(市菁英人才培养对象院内配套) （市菁英人才培养对象院内配套）
深圳市第三人民医院院内课题(G2022004) Shenzhen High-level Hospital Construction Fund(Institutional Matching for the Shenzhen Elite Talent Training Program) （G2022004）
Intramural Project of Shenzhen Third People's Hospital(G2022004) （G2022004）
