江西中医药大学学报2026，Vol.38Issue(1)：51-55,5.DOI:10.20140/j.2095-7785.2026.01.12
基于"湿热论治、内外并治"的黄白胶囊联合消痔洗剂治疗混合痔术后并发症临床观察
Clinical Observation on Huangbai Capsule Combined with Xiaozhi Lotion in the Treatment of Postoperative Complications of Mixed Hemorrhoids Based on the Therapeutic Principles of"Damp-heat Treatment,Internal and External Treatment"
摘要
Abstract
Objective:Taking"Damp-heat treatment,both internal and external treatment"as the guiding ideology to study the clinical effect of Huangbai Capsule combined with Xiaozhi Lotion on postoperative complications of mixed hemorrhoids and its influence on inflammatory factors.Methods:90 cases of mixed hemorrhoid after operation were randomly divided into three groups:Huangbai Capsule Group(30 cases),Xiaozhi Lotion Group(30 cases)and Huangbai Capsule combined with Xiaozhi Lotion Group(30 cases).The changes of anal edema,pain and bleeding were recorded on the 3rd,7th and 14th day after operation in three groups,and the statistics of TCM syndrome were completed.The granulation tissue of each group was detected by HE,and the expression of NF-κB and IFN-γ was detected by ELISA.Results:All the three groups can effectively alleviate the pain,edema,bleeding symptoms and improve the symptoms of traditional Chinese medicine mixed hemorrhoids;On the 14th day after operation,Huangbai Capsule combined with Xiaozhi Lotion Group was better than Xiaozhi Lotion Group and Huangbai Capsule Group,the difference was significant(P<0.05);The healing time of Huangbai Capsule combined with Xiaozhi Lotion group was significantly shorter than that of Xiaozhi Lotion group and Huangbai Capsule Group(P<0.05);There was no significant difference in the total effective rate.On the 14th day after operation,the expression of NF-κB and IFN-γin the three groups were all decreased,but that in the Huangbai Capsule combined with Xiaozhi Lotion group was significantly lower than that in the other two groups(P<0.05).On the 14th day after operation,the fibroblasts in the Huangbai capsule combined with Xiaozhi lotion group were found to be relatively dense and orderly,and collagen fibers and more capillary were clearly seen.Conclusion:Huangbai Capsule and Xiaozhi Lotion,guided by the theory of"Damp-heat treatment,internal and external treatment",have better effect on the postoperative complications of mixed hemorrhoids and inhibiting the expression of inflammatory factors.关键词
湿热论治/内外并治/黄白胶囊/消痔洗剂/混合痔/术后并发症/炎症因子Key words
Treatment of Damp-heat/Internal and External Treatment/Huangbai Capsule/Xiaozhi Lotion/Mixed Hemorrhoids/Postoperative Complications/Inflammatory Factor分类
医药卫生引用本文复制引用
蔡而玮,赵诚,许圳鹏,林峰..基于"湿热论治、内外并治"的黄白胶囊联合消痔洗剂治疗混合痔术后并发症临床观察[J].江西中医药大学学报,2026,38(1):51-55,5.基金项目
福建中医药大学校管科研课题优势学科专项(X2022002-专项). （X2022002-专项）
