国际眼科杂志2026，Vol.26Issue(3)：489-492,4.DOI:10.3980/j.issn.1672-5123.2026.3.22
高海拔地区配戴角膜塑形镜对近视儿童青少年眼表和睑板腺的影响
Impacts of wearing orthokeratology lenses on ocular surface and meibomian gland of children and adolescents in high-altitude areas
摘要
Abstract
•AIM:To explore the impacts of wearing orthokeratology lenses on the ocular surface and meibomian gland of children and adolescents in high-altitude areas. •METHODS:Retrospective study.Myopic children and adolescents who visited at the ophthalmology department and received orthokeratology lens from June 2023 to December 2023 were selected as orthokeratology group,and those who visited and wore regular spectacle group during the same period were selected as regular spectacle group.Then the ocular surface disease index(OSDI)score,tear meniscus height,non-invasive breakup time(NIBUT)[first NIBUT(fNIBUT),average NIBUT(avNIBUT)],and meibomian gland score were compared between the two groups before wearing lenses,and at 1,3,6,and 12 mo after wearing lenses. •RESULTS:A total of 80 children(160 eyes)with myopia were included in this study.Among them,40 cases(80 eyes)were in the orthokeratology lens group,with 25 males and 15 females and an average age of 11.33±2.76 years old,and 40 cases(80 eyes)were in the regular spectacle group,with 23 males and 17 females and an average age of 11.58±2.94 years old.The OSDI scores and tear meniscus heights showed no clear difference between two groups at various time points before and after wearing glasses(all P>0.05).The fNIBUT and avNIBUT of the orthokeratology lens group decreased compared with the regular spectacle group at 6 and 12 mo after wearing lenses,and meibomian gland score of the orthokeratology group was higher than that of the regular spectacle group at 12 mo after wearing lenses(all P<0.001).Among them,the fNIBUT and avNIBUT of the orthokeratology lenses group at 3,6,and 12 mo after wearing glasses were lower than those before wearing glasses(all P<0.05).Moreover,the meibomian gland scores of the orthokeratology lenses group at 12 mo after wearing glasses were higher than those before wearing glasses,and 1,3,and 6 mo after wearing glasses(all P<0.05),while there was no statistical difference in fNIBUT,avNIBUT,and meibomian gland score at each time point in the regular spectacle group(all P>0.05). •CONCLUSION:Long term wearing of orthokeratology lenses can shorten the NIBUT of myopic children and adolescents in high-altitude areas,and have a certain impact on their meibomian gland function.关键词
高海拔地区/角膜塑形镜/儿童青少年/眼表/睑板腺Key words
high-altitude areas/orthokeratology lens/children and adolescents/ocular surface/meibomian gland引用本文复制引用
王笃亲,马晓梅,刘雪英..高海拔地区配戴角膜塑形镜对近视儿童青少年眼表和睑板腺的影响[J].国际眼科杂志,2026,26(3):489-492,4.基金项目
2023 年青海省卫健委指导性计划项目(No.2023-wjzdx-98) Guiding Project of the Health Commission of Qinghai Province in 2023(No.2023-wjzdx-98) （No.2023-wjzdx-98）
