农药学学报2026，Vol.28Issue(1)：85-95,11.DOI:10.16801/j.issn.1008-7303.2026.0002
7-氮杂吲哚取代的2-吡啶甲酸及其甲酯衍生物的合成与除草活性
Synthesis and herbicidal activity of 7-azindolylpicolinic acids and their methyl esters derivatives
摘要
Abstract
To discover picolinic acid molecules with excellent herbicidal activity,22 new compounds of 4-amino-3,5-dicholo-6-(7-azindol-1-yl)-2-pyridinecarboxylic acids and their methyl esters derivatives were designed and synthesized.The inhibitory activities and potential herbicidal activities of the new compounds were preliminarily tested.It was found that the inhibitory activity of methyl esters on the root growth of Arabidopsis thaliana was generally better than that of corresponding picolinic acid compounds.All new compounds had good activity inhibiting Echinochloa crusgalli root growth through Petri dish test,and the pre-emergence herbicidal activity of compound VII-3 against Amaranthus retroflexus was more potent at 500 g/hm2 than picloram,most of the compounds had the same herbicidal activity at 250 g/hm2 against A.retroflexus and Chenopodium album planted in small pots in greenhouse as the control picloram,but they did not show pre/post-emergence herbicidal activity against E.crusgalli.关键词
2-吡啶甲酸/7-氮杂吲哚/合成/除草活性Key words
2-pyridindecarboxylic/7-azindole/synthesis/herbicidal activity分类
化学化工引用本文复制引用
袁潇,刘青,李会婷,韦唯,史容川,曹一明,刘尚钟,朱军..7-氮杂吲哚取代的2-吡啶甲酸及其甲酯衍生物的合成与除草活性[J].农药学学报,2026,28(1):85-95,11.基金项目
国家重点研发计划(No.2022YFD1700400). Supported by the National Key Research and Development Program of China(No.2022YFD1700400). （No.2022YFD1700400）
