华西口腔医学杂志2026，Vol.44Issue(1)：137-143,7.DOI:10.7518/hxkq.2025.2025123
磨牙切牙釉质矿化不全的临床治疗研究
Comparative study on the treatment of molar-incisor hypomineralization
摘要
Abstract
Objective This study aimed to evaluate the efficacy of different treatment methods on local plaque le-sions of incisors and the sealing of pits and fissures in first permanent molars in patients with mild molar-incisor hypo-mineralization(MIH).Methods Patients clinically diagnosed with mild MIH were selected as research subjects for a prospective clinical comparative study on the treatment of local plaque lesions in incisors and the pits and fissures of first permanent molars.Infiltrative resin and fluoride varnish were used to treat local plaque lesions on incisors.The area of local plaque lesions on incisors and lightness(L),red-green hue(a),and yellow-blue hue(b)of the lesion area were measured before treatment and at 1,3,and 6 months after treatment.The color difference value(ΔE)and tooth whiteness index(WID)were then calculated.Two meth-ods,phosphoric acid etching pit and fissure sealing and self-etching pit and fissure sealing,were used for the treatment of pits and fissures of first permanent molars.The inci-dence rate of caries,sealant retention rate,and success rate of pit and fissure sealing for the two methods were calculated at 1,3,and 6 months after treatment.Results In patients with mild MIH,local plaque lesions on incisors exhibited a significant reduction in area at 1,3,and 6 months post-treatment in the infiltrative resin group(P<0.05),whereas no sig-nificant change was observed in the fluoride application group(P>0.05).After infiltrative resin treatment,the L value and ΔE value showed a decreasing trend(P<0.05),whereas the L value in the fluoride application group did not change significantly(P>0.05).In patients with first permanent molars,the phosphoric acid etching pit and fissure sealing group exhibited superior success and retention rates at 6 months post-treatment compared with the self-etching pit and fissure sealing group(P<0.05)and a lower loss rate than the self-etching pit and fissure sealing group(P<0.05).Conclusion Infiltrative resin treatment can reduce the L value and ΔE value of local plaque lesions on incisors in patients with mild MIH.It demonstrates a significant improvement in plaque lesion area,with relatively stable effects within 6 months.Phosphoric acid etching is recommended for the pit and fissure sealing of first permanent molars in patients with mild MIH.关键词
磨牙切牙釉质矿化不全/切牙局部斑块病损/渗透树脂/第一恒磨牙/窝沟封闭Key words
molar-incisor hypomineralisation/local plaque lesions of incisors/infiltrative resin/first permanent molar/pit and fissure sealant分类
医药卫生引用本文复制引用
单小霞,杨巧韵,杨兴花,杨雨欣,马亚楠,赵子昂,李睿敏..磨牙切牙釉质矿化不全的临床治疗研究[J].华西口腔医学杂志,2026,44(1):137-143,7.基金项目
China Oral Health Foundation(A2021-135) （A2021-135）
Natural Science Foundation of Ningxia Province(2024AAC-02076) 中国牙病防治基金(A2021-135) （2024AAC-02076）
宁夏自然科学基金(2024AAC02076) （2024AAC02076）
