南京医科大学学报（自然科学版）2026，Vol.46Issue(2)：299-308,10.DOI:10.7655/NYDXBNSN250853
肺移植术后闭塞性细支气管炎的研究进展
Research progress on bronchiolitis obliterans syndrome after lung transplantation
摘要
Abstract
Lung transplantation(LTx)is an effective treatment for end-stage lung disease,significantly prolonging patient survival and improving quality of life.However,bronchiolitis obliterans syndrome(BOS),which represents a frequent manifestation of chronic rejection following LTx,significantly compromises long-term patient survival.Consequently,early diagnosis and comprehensive treatment are crucial for improving prognosis,while exploration of individualized therapeutic strategies is needed to optimize clinical management.This review comprehensively examines the clinical manifestations,diagnostic approaches,pathogenesis,risk factors,therapeutic strategies,and prognostic characteristics of BOS,aiming to provide evidence-based guidance for clinical management and future research directions.关键词
肺移植/闭塞性细支气管炎综合征/慢性排斥反应Key words
lung transplantation/bronchiolitis obliterans syndrome/chronic allograft dysfunction分类
医药卫生引用本文复制引用
乔烨甜,李小杉,吴波..肺移植术后闭塞性细支气管炎的研究进展[J].南京医科大学学报（自然科学版）,2026,46(2):299-308,10.基金项目
无锡市"双百"中青年医疗卫生拔尖人才项目(BJ2023016) （BJ2023016）
无锡市人民医院雁阵人才项目(2024-YZ-KDTR-WB-2024) （2024-YZ-KDTR-WB-2024）
