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基因组选择技术在家畜育种中的应用

闫成琪 冯炼君 李发弟 王维民 赵源 田慧彬 张煜坤 李晓龙 张琪 蒲萌茹 高磊 肖子越

农业生物技术学报2026,Vol.34Issue(3):480-490,11.
农业生物技术学报2026,Vol.34Issue(3):480-490,11.DOI:10.3969/j.issn.1674-7968.2026.03.003

基因组选择技术在家畜育种中的应用

Application of Genomic Selection Techniques in Livestock Breeding

闫成琪 1冯炼君 1李发弟 1王维民 1赵源 1田慧彬 1张煜坤 1李晓龙 1张琪 1蒲萌茹 1高磊 1肖子越1

作者信息

  • 1. 兰州大学草地农业科技学院/草种创新与草地农业生态系统全国重点实验室,兰州 730020
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摘要

Abstract

With the deep integration of genomics and quantitative genetics,the practical application of genomic selection techniques in livestock breeding continues to expand.Particularly since the turn of the 21st century,iterative advancements in sequencing technology have reduced the cost of whole-genome genotyping,accelerating the adoption of genomic selection across a broader range of livestock species.This approach demonstrates significant potential in enhancing the production performance of selected populations,strengthening disease resistance within herds,and optimising breeding strategies.This paper provided a systematic review of the research progress and application of genomic selection technology in livestock breeding.The full paper revolves around:(1)the principles and development history of the technology,elucidating the methodological framework for genome-wide molecular marker screening and genetic effect assessment;(2)the methods and models used in the technology,involving traditional genomic estimated breeding value(GEBV)assessment methods such as best linear unbiased prediction(BLUP)and Bayesian method,as well as new methods of machine learning,such as support vector machines and random forests;(3)the methods to improve the accuracy of genome selection,considerations of across breeds,combining new methods and approaches such as genome-wide association analysis to increase the reliability and usability of the technology;(4)analysis of the current status of application,focusing on the great potential of the technology in improving the production performance of livestock,breeding for disease resistance and optimising breeding strategies.This paper constructed a three-dimensional analysis system of technology principle-application practice-trend development to provide theoretical support for the development of livestock breeding technology in the context of smart agriculture.

关键词

基因组选择技术/家畜/育种应用/育种值评估

Key words

Genomic selection technology/Livestock/Breeding applications/Breeding value evaluation

分类

农业科技

引用本文复制引用

闫成琪,冯炼君,李发弟,王维民,赵源,田慧彬,张煜坤,李晓龙,张琪,蒲萌茹,高磊,肖子越..基因组选择技术在家畜育种中的应用[J].农业生物技术学报,2026,34(3):480-490,11.

基金项目

国家重点研发计划(2023YFF1001000) (2023YFF1001000)

甘肃省研产融合科技赋能计划(25FNNH001) (25FNNH001)

甘肃省科技计划项目(25YFNA017 ()

22ZD6NC069) ()

武威市科技重大专项(WW23A03ZDQ001) (WW23A03ZDQ001)

金昌市重点科技计划项目(2024JC00152) (2024JC00152)

农业生物技术学报

1674-7968

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