实用肝脏病杂志2026，Vol.29Issue(1)：81-84,4.DOI:10.3969/j.issn.1672-5069.2026.01.021
球囊阻断逆行经静脉闭塞术治疗乙型肝炎肝硬化并发胃静脉曲张患者疗效研究
Efficacy of balloon-occluded retrograde transvenous obliteration in the treatment of patients with hepatitis B-induced liver cirrhosis and gastric varices
摘要
Abstract
Objective This study aimed to retrospectively evaluate the efficacy and safety of balloon-occluded retrograde transvenous obliteration(BRTO)in patients with hepatitis B-induced liver cirrhosis(LC)complicated by gastric varices(GV).Methods A total of 101 patients with hepatitis B-induced LC and complicated GV were encountered in our hospital between January 2022 and June 2024,and were randomly divided into two groups,underwent BRTO in observation group(n=51)or transjugular intrahepatic portosystemic shunt(TIPS)in control group(n=50).All patients were followed-up for one year after operation.Results By end of three-month of follow-up,eradication rate of GV in the observation group was 84.3％and second BRTO eradicated all GV,while GV disappeared in 5 cases(10.0％,P＜0.05)in the control;by end of six-month of follow-up,two patients in the observation and four patients in the control died;by end of one-year of follow-up,three cases in BRTO-treated patients and five cases in TIPS-treated died;after operations,the liver function tests and hypersplenism didn't improved and the related parameter were not significantly different between the two groups(P＞0.05).Conclusion BRTO demonstrates safe and a favorable GV eradication rate in the treatment of patients with hepatitis B-induced LC,which might needs sophisticated procedural skills,and the long-term efficacy on prophylactic GV bleeding is still observed.关键词
肝硬化/胃静脉曲张/球囊阻断逆行经静脉闭塞术/经颈静脉肝内门体分流术/治疗Key words
Liver cirrhosis/Gastric varices/Balloon-occluded retrograde transvenous obliteration/Transjugular intrahepatic portosystemic shunt/Therapy引用本文复制引用
段后张,郑扬,陈旭峰,汤小龙,汪程龙..球囊阻断逆行经静脉闭塞术治疗乙型肝炎肝硬化并发胃静脉曲张患者疗效研究[J].实用肝脏病杂志,2026,29(1):81-84,4.基金项目
江苏省科技厅社会发展面上基金资助项目(编号:BE2020775) （编号:BE2020775）
