中国肛肠病杂志2026，Vol.46Issue(2)：15-18,4.
术后早期炎性肠梗阻中药灌肠组方用药规律数据挖掘研究
Data Mining Study on Medication Regularity of Chinese Medicinal Retention Enema Formulas for Early Postoperative Inflammatory Small Bowel Obstruction
摘要
Abstract
Objective To analyze the formulation and medication rules of Chinese medicinal retention enema for early postoperative inflammatory small bowel obstruction(EPISBO)using data mining technol-ogy.Methods Relevant literatures on the treatment of EPISBO with Chinese medicinal retention enema were retrieved from CNKI,WanFang and VIP databases.According to the inclusion and exclusion criteria,a formula database of Chinese medicinal retention enema for EPISBO was constructed and entered into IBM SPSS Modeler 18.0 and IBM SPSS Statistics 25.0 for association rule analysis and cluster analysis of the data.Results A total of 50 Chinese medicinal formulas were included,involving 64 types of Chinese medici-nals.The efficacy of Chinese medicinals were mainly purgation,regulating qi,clearing heat,tonifying defi-ciency,activating blood and resolving blood stasis.Total 20 types of Chinese medicinals appeared≥7 times,among which Dahuang(Rhei Radix Et Rhizoma),Houpo(Magnoliae Officinalis Cortex),Zhishi(Aurantii Fructus Immaturus),Mangxiao(Natrii Sulfas),and Taoren(Persicae Semen)appeared more frequently.The properties were mainly cold,slightly cold,warm and slightly warm,the flavors were mainly bitter and pun-gent,and the meridian tropisms were mainly the spleen,stomach,large intestine and liver meridians.Total 12 association rules of medicinal groups were obtained by association rule analysis,and 4 types of core formulas were obtained through cluster analysis.Conclusion In the treatment of EPISBO,purgation and removing accumulation to dredge Fu-organs are the main methods.The core formula is Dachengqi Decoction,combined with the methods of resolving dampness,promoting qi movement,activating blood and resolving blood stasis,tonifying deficiency and clearing heat to treat both the symptoms and the root causes.关键词
术后早期炎性肠梗阻/中药保留灌肠/数据挖掘/用药规律/聚类分析Key words
Early postoperative inflammatory small bowel obstruction/Chinese medicinal retention enema/Data mining/Medication regularity/Cluster analysis引用本文复制引用
吴文杰,胡响当,李磊磊,黄晓旭,黄启宣,李自瑶..术后早期炎性肠梗阻中药灌肠组方用药规律数据挖掘研究[J].中国肛肠病杂志,2026,46(2):15-18,4.基金项目
湖南省卫生健康委卫生科研课题(C202304017114) （C202304017114）
湖南省中医药管理局委托课题(D2023008) （D2023008）
湖南中医药大学校级科研基金与联合基金重点项目(2021XJJJ054) （2021XJJJ054）
湖南省自然科学基金高校联合基金项目(2025JJ90122) （2025JJ90122）
湖南省中医药管理局课题(B2024094) （B2024094）
湖南中医药大学校院联合基金项目(2024XYLH057) （2024XYLH057）
