心理科学进展2026，Vol.34Issue(3)：441-460,20.DOI:10.3724/SP.J.1042.2026.0441
同步TMS-EEG技术在心理学研究中的应用
Applications of TMS-EEG in psychological research:Neurophysiological assessment,causal neural mechanisms,and closed-loop modulation
摘要
Abstract
Transcranial magnetic stimulation-electroencephalography(TMS-EEG)is a technique that synchronously integrates transcranial magnetic stimulation with electroencephalographic recording.It allows the capture of instantaneous neurophysiological responses evoked by stimulation and enables the implementation of state-dependent,precisely timed brain interventions guided by real-time neural monitoring.Over the past decade,TMS-EEG has become a crucial approach for neurophysiological assessment,causal neural mechanisms,and closed-loop brain modulation.Yet these three application modes differ substantially in their underlying mechanisms and methodological frameworks,and a systematic synthesis remains lacking.This review surveys relevant research from the past decade,organized along three thematic lines—neural assessment,mechanistic elucidation,and closed-loop modulation.We clarify the fundamental principles and operational mechanisms of each mode and summarize representative empirical findings.Finally,we highlight current challenges and outline future research directions,aiming to provide clear theoretical reference and practical guidance for researchers employing synchronous TMS-EEG in cognitive and clinical neuroscience.关键词
同步经颅磁刺激-脑电图/神经生理评估/虚拟损伤/因果性神经机制/闭环调控Key words
TMS-EEG/neurophysiological assessment/virtual lesion/causal neural mechanisms/closed-loop modulation分类
社会科学引用本文复制引用
郭新宇,汤煜尧,张丹丹..同步TMS-EEG技术在心理学研究中的应用[J].心理科学进展,2026,34(3):441-460,20.基金项目
国家自然科学基金面上项目(32271102)支持. （32271102）
