医学新知2026，Vol.36Issue(1)：103-109,7.DOI:10.12173/j.issn.1004-5511.202501003
微小RNA在结直肠癌上皮间质转化中的作用与研究进展
Research progress on the role of microRNA in epithelial-mesenchymal transition of colorectal cancer
张涛 1李辉龙 2冯静 1陈淼3
作者信息
- 1. 四川大学华西医院临床药学部(成都 610041)
- 2. 重庆市巴南区接龙镇中心卫生院外科(重庆 401344)
- 3. 遂宁市检验检测中心(四川 遂宁 629000)
- 折叠
摘要
Abstract
Colorectal cancer(CRC)is the third most common cancer globally,with an incidence rate ranked just behind lung cancer and breast cancer in women.Epithelial-mesenchymal transition(EMT)enhances the migratory and invasive abilities of tumor cells but is also closely associated with tumor recurrence and drug resistance.MicroRNAs(miRNAs)are a class of non-coding RNAs that regulate the EMT process through various mechanisms and pathways.Therefore,this review aims to summarize the roles and research progress of miRNAs in the regulation of EMT in CRC,providing new insights into the complex regulation of EMT and offering potential strategies for the prevention and treatment of CRC metastasis.关键词
结直肠癌/上皮间质转化/微小RNA/耐药性/天然化合物Key words
Colorectal cancer/Epithelial-mesenchymal transition/MicroRNA/Drug resistance/Natural compound分类
医药卫生引用本文复制引用
张涛,李辉龙,冯静,陈淼..微小RNA在结直肠癌上皮间质转化中的作用与研究进展[J].医学新知,2026,36(1):103-109,7.
