中国现代医学杂志2026，Vol.36Issue(4)：103-107,5.DOI:10.3969/j.issn.1005-8982.2026.04.017
Nd:YAG激光联合普萘洛尔治疗颌面部血管瘤的临床疗效观察
Clinical efficacy of Nd:YAG laser combined with propranolol in the treatment of maxillofacial hemangiomas
摘要
Abstract
Objective To investigate the clinical efficacy of Nd:YAG laser combined with propranolol in treating maxillofacial hemangiomas.Methods Sixty patients with maxillofacial hemangiomas admitted to Xing'an League People's Hospital between May 2020 and May 2023 were selected and randomly divided into the control group and the observation group(30 patients each)using a random number table.The control group received Nd:YAG laser therapy alone,while the observation group was additionally administered propranolol.Treatment efficacy,hemodynamic parameters,vascular endothelial growth factor(VEGF)levels,degree of tumor regression,adverse reactions,and recurrence rates were compared between groups.Results The overall effective rate of treatment was higher in the observation group compared to the control group(P<0.05).The differences in peak blood flow,resistance index,levels of VEGF and basic fibroblast growth factor,and hemangioma activity scale scores before and after treatment were greater in the observation group than in the control group(P<0.05).There was no statistically significant difference in the overall incidence of adverse reactions between the two groups(P>0.05).After a 2-year follow-up,the recurrence rate was lower in the observation group than in the control group(P<0.05).Conclusion Combining Nd:YAG laser therapy with propranolol yields significant efficacy in treating maxillofacial hemangiomas.This approach improves VEGF levels and hemodynamic parameters,promotes tumor regression,exhibits a low recurrence rate,and demonstrates a good safety profile.关键词
颌面部血管瘤/Nd:YAG激光/普萘洛尔/疗效Key words
maxillofacial hemangiomas/Nd:YAG laser/propranolol/efficacy分类
医药卫生引用本文复制引用
宋景东,叶荫,薄向宇,李婷楠,张雪..Nd:YAG激光联合普萘洛尔治疗颌面部血管瘤的临床疗效观察[J].中国现代医学杂志,2026,36(4):103-107,5.基金项目
内蒙古自治区自然科学基金面上项目(No:2024MS08063) （No:2024MS08063）
兴安盟科技计划项目(No:MB202217) （No:MB202217）
