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基于nnUNet多模型集成的超声心动图四腔室分割

魏洁 金鑫 刘永星 冯娜

中国医学装备2026,Vol.23Issue(2):27-32,6.
中国医学装备2026,Vol.23Issue(2):27-32,6.DOI:10.3969/j.issn.1672-8270.2026.02.006

基于nnUNet多模型集成的超声心动图四腔室分割

Segmentation of cardiac four-chamber of echocardiography based on integration of nnUNet multi-model

魏洁 1金鑫 2刘永星 3冯娜4

作者信息

  • 1. 空军军医大学生物医学工程学系 西安 710032||空军军医大学西京医院创新研究院 西安 710032
  • 2. 东部战区总医院秦淮医疗区医学工程科 南京 210001
  • 3. 空军第九八六医院医学工程科 西安 710054
  • 4. 空军军医大学基础医学院生理与病理生理学教研室 西安 710032
  • 折叠

摘要

Abstract

Objective:To propose a multi-model ensemble framework based on no-new-Net(MME-nnUNet)on the basis of the problems of low resolution,noise interference,and insufficient annotation in the precise segmentation of echocardiograms for cardiac four-chamber,so as to improve the accuracy and robustness of segmentation.Methods:A total of 293 videos of apical four-chamber view in public dataset of cardiac ultrasound(CardiacUDC),which was issued in 2023 by Guangdong Provincial People's Hospital,were selected.The quality of data was optimized through multi-stage preprocessing(manual screening,morphological operation).Using the Residual U-shaped network(ResUNet)as the baseline model to construct a two dimension(2D)nnUNet model to extract features of single-frame images,and to generate pseudo-labels to relieve the issue of insufficient annotations of three dimension(3D)data.A 3D nnUNet model was designed to capture spatiotemporal correlations among consecutive frames.The optimized segmentation results of post-processing were preserved through integrated the outputs of 2D and 3D multi-models,and adopted the largest connected area.Results:In the test set,the Dice similarity coefficient(DSC)of MME-nnUNet was 0.946 6,and the average surface distance(ASD)was 0.435 2 mm,and the 95%Hausdorff distance(HD95)was 3.959 6 mm,which increased 2.89%,and decreased 0.5214 mm and 3.2794 mm than the baseline ResUNet model.Conclusion:The enhancement of DSC,and the decreases of ASD and HD95 through integrates the advantages of 2D and 3D models and through semi-supervised data augmentation and optimization of dynamic post-processing demonstrate that MME-nnUNet can enhance the accuracy of the segmentation for four cardiac chambers,which can provide reliably technical support for cardiac function assessment,and diagnosis and treatment for disease.

关键词

超声心动图/心脏分割/无需新网络(nnUNet)/多模型集成/半监督学习

Key words

Echocardiography/Segmentation of heart/No-new-Net(nnUNet)/Multi-model ensemble/Semi-supervised learning

分类

医药卫生

引用本文复制引用

魏洁,金鑫,刘永星,冯娜..基于nnUNet多模型集成的超声心动图四腔室分割[J].中国医学装备,2026,23(2):27-32,6.

基金项目

西京创新研究院联合基金项目(LHJJ24YG13) Joint Founding Project of innovation Research Institute,Xijing Hospital(LHJJ24YG13) (LHJJ24YG13)

中国医学装备

1672-8270

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