中国实用妇科与产科杂志2026，Vol.42Issue(1)：24-28,5.DOI:10.19538/j.fk2026010106
子宫内膜癌规范化诊治中的个体化
Individualization in standardized diagnosis and treatment of endometrial cancer
摘要
Abstract
Endometrial cancer(EC)is the most common gynecologic malignancy in developed countries,and its incidence has been steadily increasing in recent years in China,with a trend toward younger onset.With the updates of international guidelines,the diagnosis,treatment and follow-up of EC have entered an era of high standardization.However,EC exhibits marked biological heterogeneity in clinical practice,and reliance solely on clinicopathological factors is insufficient in accurately identifying prognostic differences and predicting therapeutic benefit.Therefore,the introduction of individualized strategies on the basis of standardized management has become an inevitable trend.The TCGA classification has established the framework for the molecular era of EC,with distinct molecular subtypes showing significant prognostic differences and providing guidance for the selection of chemotherapy,radiotherapy and immunotherapy.In recent years,rapid advances in researches on the tumor immune microenvironment(TIME)have further clarified the impact of different immune infiltration patterns on treatment responses.This review summarizes the current status and recent advances in standardized diagnosis and treatment of EC,with a particular focus on individualized strategies driven by molecular typing,immune characteristics,and multi-omics integration,aiming to provide references for clinical practice.关键词
子宫内膜癌/诊治/规范化/个体化/分子分型Key words
endometrial cancer/diagnosis and treatment/standardization/individualization/molecular typing分类
医药卫生引用本文复制引用
李立伟,董阳阳,王建六..子宫内膜癌规范化诊治中的个体化[J].中国实用妇科与产科杂志,2026,42(1):24-28,5.基金项目
首都卫生发展科研专项(2022-1-4081) Special Scientific Research Project for Health Development in the Capital(2022-1-4081) （2022-1-4081）
