中国中西医结合急救杂志2025，Vol.32Issue(6)：726-732,7.DOI:10.3969/j.issn.1008-9691.2025.06.016
体外膜肺氧合对患者存活率影响的Meta分析
A Meta-analysis of the impact of extracorporeal membrane oxygenation on patient survival rate
摘要
Abstract
Objective To systematically evaluate the impact of extracorporeal membrane oxygenation(ECMO)support on the short-term and long-term survival rate of patients with acute respiratory failure,heart failure or cardiac arrest.Methods Databases including PubMed of the National Library of Medicine,Web of Science,the Cochrane Library,China National Knowledge Infrastructure(CNKI)and Wanfang were searched for studies on the survival rate of patients treated with ECMO,with the time range from January 2020 to October 2022.The Chinese search terms included survival rate,mortality,outcome,prognosis;the English search terms included extracorporeal membrane oxygenation,ECMO,survival rate,mortality,outcome,etc.During the literature screening process,two researchers independently assessed the relevant literature,and a Meta-analysis was conducted to evaluate the impact of ECMO treatment on the overall survival rate and discharge survival rate of patients,as well as the survival rates and short-term survival rates of patients with pulmonary and cardiac causes using ECMO,and conducted an assessment of the risk of bias for the included studies.Results The overall survival rate of patients treated with ECMO was 52.3%[95%confidence interval(95%CI)was 0.473-0.566,P<0.001].Subgroup analysis showed that the short-term survival rate after ECMO initiation was 57.6%(95%CI was 0.502-0.650,P<0.001),the discharge survival rate for ECMO was 51.3%(95%CI was 0.473-0.553,P<0.001).Meanwhile,the survival rate of patients with pulmonary disease treated with ECMO was 51.3%(95%CI was 0.468-0.551,P=0.008);and that of patients with cardiogenic disease treated with ECMO was 48.1%(95%CI was 0.442-0.489,P<0.001).Conclusions The overall survival rate of ECMO treatment is not high.There are statistically significant differences in the survival rates of patients with different diseases at different time points after ECMO treatment.关键词
体外膜肺氧合/存活率/Meta分析Key words
Extracorporeal membrane oxygenation/Survival rate/Meta-analysis引用本文复制引用
周涛,田静,李轶江,刘洋,李鸣涛,陈静瑜,许红阳..体外膜肺氧合对患者存活率影响的Meta分析[J].中国中西医结合急救杂志,2025,32(6):726-732,7.基金项目
江苏省无锡市"太湖人才计划"高端医学专家团队项目(2021THRC-TD-ZZYXK-2021) The High-Level Medical Expert Team Project Under the"Taihu Lake Talent Plan"of Wuxi City,Jiangsu Province(2021THRC-TD-ZZYXK-2021) （2021THRC-TD-ZZYXK-2021）
