中国中医眼科杂志2026,Vol.36Issue(2):187-190,4.DOI:10.13444/j.cnki.zgzyykzz.2026.02.017
中医药治疗糖尿病视网膜病变作用机制的研究进展
Research Progress on the Mechanisms of Traditional Chinese Medicine in the Treat-ment of Diabetic Retinopathy
摘要
Abstract
Diabetic retinopathy(DR)is one of the common microvascular complications of diabetes,severely affecting patients'vision.In recent years,Traditional Chinese Medicine(TCM)has shown unique advantages in the prevention and treatment of DR through its multi-target and holistic regulatory effects.This paper reviews the mechanisms of TCM in the prevention and treat-ment of DR from four aspects:Anti-inflammatory,antioxidant stress,modulation of gut microbiota,and downregulation of vascular endothelial growth factor(VEGF)expression.It was found that mul-tiple TCM monomers and classic formulas can effectively delay the progression of DR,and play a synergistic role in improving retinal microcirculation,regulating blood glucose,and lipids.It is pointed out that TCM,through the therapeutic principles of"activating blood circulation and re-moving blood stasis"and"tonifying Qi and nourishing Yin",exerts a multi-pathway synergistic ef-fect,showing unique clinical value in the prevention and treatment of DR.However,practical chal-lenges remain,including inconsistent TCM syndromes,weak mechanistic research,and lack of ob-jective evaluation systems.Future efforts should focus on integrating TCM and Western Medicine,establishing standardized diagnosis and treatment protocols,and further exploring the mechanisms of TCM to promote the precision and systematic development of DR prevention and treatment.关键词
糖尿病视网膜病变/作用机制/中医药/靶点Key words
diabetic retinopathy/mechanism of action/Traditional Chinese Medicine/targets分类
医药卫生引用本文复制引用
仇文静,邹红..中医药治疗糖尿病视网膜病变作用机制的研究进展[J].中国中医眼科杂志,2026,36(2):187-190,4.基金项目
1国家自然科学基金项目(81874384) 2上海市浦东新区卫健委联合攻关项目(PW2021D-03) (81874384)