中国中医基础医学杂志2026，Vol.32Issue(2)：329-333,5.
基于伏邪理论的溃疡性结肠炎复发病机认识
Understanding the Pathogenesis of Ulcerative Colitis Recurrence Based on the Latent Pathogen Theory
摘要
Abstract
Latent pathogens,as pathogenic factors that remain hidden in the body after infection and cause delayed onset,are the core cause of recurrent ulcerative colitis(UC).The characteristics of latency,progression,and accumulation of latent pathogens align with the pathogenesis of UC,which is"deficiency of vital Qi as the root,and damp-heat and blood stasis as the manifestation".This perspective also correlates with pathological mechanisms confirmed by modern medicine,such as mucosal barrier damage and persistent activation of tissue-resident memory cells.Based on the latent pathogen theory,this paper explores the evolutionary patterns of UC recurrence and corresponding treatment principles.It also proposes the"new eight principles of syndrome differentiation for spleen and stomach diseases"as a guideline for syndrome differentiation and treatment during remission,offering new insights into the prevention and treatment of UC recurrence with traditional Chinese medicine.关键词
溃疡性结肠炎/伏邪/复发/组织驻留记忆T细胞Key words
Ulcerative colitis/Latent pathogens/Recurrence/Tissue-resident memory T cells分类
医药卫生引用本文复制引用
王忻彤,张佳琪,唐旭东..基于伏邪理论的溃疡性结肠炎复发病机认识[J].中国中医基础医学杂志,2026,32(2):329-333,5.基金项目
国家自然科学基金项目(82341233) （82341233）
中国中医科学院西苑医院学术经验继承项目(0203064) （0203064）
