中国药理学通报2026,Vol.42Issue(2):235-239,5.DOI:10.12360/CPB202507104
倍半萜内酯类化合物的神经保护效应与机制研究进展
Progress on neuroprotective effects and mechanisms of sesquiterpene lactones
摘要
Abstract
Sesquiterpene lactones are a diverse class of natural compounds predominantly found in the asteraceae family,with extensive sources in traditional herbal medicines.These com-pounds are characterized by three isoprene units and have been recognized for their wide range of biological activities,includ-ing antitumor,antiviral,antibacterial,and antidiabetic proper-ties.Recent cellular and animal studies have increasingly high-lighted the neuroprotective effects of sesquiterpene lactones.This review aims to summarize and critically evaluate the latest advancements in the neuroprotective mechanisms of SLs,pro-viding valuable insights for the further research and develop-ment of SLs-based therapeutic agents.关键词
倍半萜内酯/神经退行性疾病/抗神经炎症/神经保护/脑损伤/生物学活性Key words
sesquiterpene lactones/neurodegenerative dis-eases/anti-neurotic inflammation/neuroprotection/brain dam-age/biological activity分类
医药卫生引用本文复制引用
谢丽云,姜秀芳,朱玲玲..倍半萜内酯类化合物的神经保护效应与机制研究进展[J].中国药理学通报,2026,42(2):235-239,5.基金项目
四大慢病重大专项(No 2023ZD0505300) (No 2023ZD0505300)