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倍半萜内酯类化合物的神经保护效应与机制研究进展

谢丽云 姜秀芳 朱玲玲

中国药理学通报2026,Vol.42Issue(2):235-239,5.
中国药理学通报2026,Vol.42Issue(2):235-239,5.DOI:10.12360/CPB202507104

倍半萜内酯类化合物的神经保护效应与机制研究进展

Progress on neuroprotective effects and mechanisms of sesquiterpene lactones

谢丽云 1姜秀芳 2朱玲玲1

作者信息

  • 1. 南华大学衡阳医学院,军事科学院军事医学研究院研究生协作培养基地,湖南 衡阳 421001||军事科学院军事医学研究院,北京 100850
  • 2. 军事科学院军事医学研究院,北京 100850
  • 折叠

摘要

Abstract

Sesquiterpene lactones are a diverse class of natural compounds predominantly found in the asteraceae family,with extensive sources in traditional herbal medicines.These com-pounds are characterized by three isoprene units and have been recognized for their wide range of biological activities,includ-ing antitumor,antiviral,antibacterial,and antidiabetic proper-ties.Recent cellular and animal studies have increasingly high-lighted the neuroprotective effects of sesquiterpene lactones.This review aims to summarize and critically evaluate the latest advancements in the neuroprotective mechanisms of SLs,pro-viding valuable insights for the further research and develop-ment of SLs-based therapeutic agents.

关键词

倍半萜内酯/神经退行性疾病/抗神经炎症/神经保护/脑损伤/生物学活性

Key words

sesquiterpene lactones/neurodegenerative dis-eases/anti-neurotic inflammation/neuroprotection/brain dam-age/biological activity

分类

医药卫生

引用本文复制引用

谢丽云,姜秀芳,朱玲玲..倍半萜内酯类化合物的神经保护效应与机制研究进展[J].中国药理学通报,2026,42(2):235-239,5.

基金项目

四大慢病重大专项(No 2023ZD0505300) (No 2023ZD0505300)

中国药理学通报

1001-1978

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