中国卒中杂志2026，Vol.21Issue(1)：55-64,10.DOI:10.3969/j.issn.1673-5765.2026.01.006
急性缺血性卒中静脉溶栓中外周血炎症指标与预后的研究进展
Research Progress on Peripheral Blood Inflammatory Indices and Prognosis in Intravenous Thrombolysis for Acute Ischemic Stroke
摘要
Abstract
Intravenous thrombolysis is an important reperfusion therapy for acute ischemic stroke(AIS).However,some patients still face challenges such as poor functional prognosis and increased risk of bleeding after intravenous thrombolysis.Inflammatory responses play a crucial role in the pathophysiological process of AIS.They not only contribute to the occurrence and development of ischemic brain injury,but also affect the efficacy and safety of intravenous thrombolysis.Due to their convenience,cost-effectiveness,and ability to be dynamically monitored,peripheral blood inflammatory indices have shown significant potential value in prognostic assessment of AIS patients.This article systematically elucidates the mechanisms of inflammatory responses after AIS onset and the research progress of related anti-inflammatory therapies.It also reviews the associations between commonly used inflammatory indices in intravenous thrombolysis(such as the neutrophil-to-lymphocyte ratio,systemic inflammatory response index,and platelet-to-lymphocyte ratio)and patient prognosis,providing a reference for selecting potential beneficiaries of anti-inflammatory therapy in AIS based on inflammatory indices.关键词
急性缺血性卒中/炎症指标/静脉溶栓Key words
Acute ischemic stroke/Inflammatory index/Intravenous thrombolysis分类
医药卫生引用本文复制引用
何丹丹,李姝雅..急性缺血性卒中静脉溶栓中外周血炎症指标与预后的研究进展[J].中国卒中杂志,2026,21(1):55-64,10.基金项目
国家自然科学基金青年科学基金项目(B类)(82522025) （B类）
