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Neutralization of Crimean-Congo hemorrhagic fever pseudotyped virions with heavy chain antibodies

Kewen Qian Yu Zhang Zhihao Li Wei Ye Yue Cui Zheng Zhu Zhengshan Chen Jianrong Wang Jin Han Ping Huang Pu Fan Peng Lv Ting Fang Guanying Zhang Changming Yu Yunzhu Dong Wujian Li Fanglin Zhang Xiangyang Chi

Virologica Sinica2025，Vol.40Issue(6)：P.1021-1036,16.

Virologica Sinica2025，Vol.40Issue(6)：P.1021-1036,16.DOI:10.1016/j.virs.2025.12.001

Neutralization of Crimean-Congo hemorrhagic fever pseudotyped virions with heavy chain antibodies

Kewen Qian ¹Yu Zhang ¹Zhihao Li ²Wei Ye ³Yue Cui ¹Zheng Zhu ¹Zhengshan Chen ¹Jianrong Wang ¹Jin Han ¹Ping Huang ¹Pu Fan ¹Peng Lv ¹Ting Fang ¹Guanying Zhang ¹Changming Yu ¹Yunzhu Dong ¹Wujian Li ⁴Fanglin Zhang ³Xiangyang Chi¹

作者信息

1. Academy of Military Medical Sciences,Beijing 100071,China
2. Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei 230031,China Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases,Hefei 230026,China
3. Department of Microbiology,Air Force Medical University:Fourth Military Medical University,Xi''an 710032,China
4. Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei 230031,China Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei 230031,China
折叠

摘要

关键词

Crimean-Congo hemorrhagic fever virus(CCHFV)/Heavy chain antibodies/VHH-Fc antibodies/Pseudovirus/Virus-like particles(VLPs)

分类

医药卫生

引用本文复制引用

Kewen Qian,Yu Zhang,Zhihao Li,Wei Ye,Yue Cui,Zheng Zhu,Zhengshan Chen,Jianrong Wang,Jin Han,Ping Huang,Pu Fan,Peng Lv,Ting Fang,Guanying Zhang,Changming Yu,Yunzhu Dong,Wujian Li,Fanglin Zhang,Xiangyang Chi..Neutralization of Crimean-Congo hemorrhagic fever pseudotyped virions with heavy chain antibodies[J].Virologica Sinica,2025,40(6):P.1021-1036,16.

基金项目

supported by the National Natural Science Foundation of China(grant no.82522044). （grant no.82522044）

Virologica Sinica

ISSN：1674-0769

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