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Gut microecology empowers cancer immunotherapy:commensal microbiota-mediated mechanisms and translational prospects of PD-1/PD-L1 therapy

Sifan Li Chang Che Yelu Zhou Daiming Fan Xue Bai Yuanyuan Lu Xiaodi Zhao

Cancer Biology & Medicine2026，Vol.23Issue(1)：P.60-77,18.

Cancer Biology & Medicine2026，Vol.23Issue(1)：P.60-77,18.DOI:10.20892/j.issn.2095-3941.2025.0347

Gut microecology empowers cancer immunotherapy:commensal microbiota-mediated mechanisms and translational prospects of PD-1/PD-L1 therapy

Sifan Li ¹Chang Che ¹Yelu Zhou ¹Daiming Fan ¹Xue Bai ¹Yuanyuan Lu ¹Xiaodi Zhao¹

作者信息

1. State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and National Clinical Research Center for Digestive Diseases,Xijing Hospital of Digestive Diseases,Fourth Military Medical University,Xi’an 710032,China
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摘要

关键词

Gut microbiota/immune checkpoint inhibitors/commensal microbiota/PD-1/PD-L1/fecal microbiota transplantation

分类

医药卫生

引用本文复制引用

Sifan Li,Chang Che,Yelu Zhou,Daiming Fan,Xue Bai,Yuanyuan Lu,Xiaodi Zhao..Gut microecology empowers cancer immunotherapy:commensal microbiota-mediated mechanisms and translational prospects of PD-1/PD-L1 therapy[J].Cancer Biology & Medicine,2026,23(1):P.60-77,18.

基金项目

supported by grants from the National Natural Science Foundation of China(Grant Nos.82222058,82425046,and 82273142). （Grant Nos.82222058,82425046,and 82273142）

Cancer Biology & Medicine

ISSN：2095-3941

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