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Polydatin alleviates mitochondrial damage and apoptosis of lung epithelial cells by inhibiting toll-like receptor 4-dependent macrophage activation in asthma

Guangxing Li Ruobai Liu Chang Xu Jianing Yang Yilan Song Li Li Jingzhi Jiang Liangchang Li Chongyang Wang Guanghai Yan

Animal Models and Experimental Medicine2026，Vol.9Issue(1)：P.89-102,14.

Animal Models and Experimental Medicine2026，Vol.9Issue(1)：P.89-102,14.DOI:10.1002/ame2.70100

Polydatin alleviates mitochondrial damage and apoptosis of lung epithelial cells by inhibiting toll-like receptor 4-dependent macrophage activation in asthma

Guangxing Li ¹Ruobai Liu ¹Chang Xu ¹Jianing Yang ¹Yilan Song ¹Li Li ¹Jingzhi Jiang ¹Liangchang Li ¹Chongyang Wang ²Guanghai Yan²

作者信息

1. Jilin Key Laboratory for Immune and Targeting Research on Common Allergic Diseases,Yanbian University,Yanji,P.R.China Department of Anatomy,Histology and Embryology,Yanbian University Medical College,Yanji,P.R.China
2. Jilin Key Laboratory for Immune and Targeting Research on Common Allergic Diseases,Yanbian University,Yanji,P.R.China Department of Anatomy,Histology and Embryology,Yanbian University Medical College,Yanji,P.R.China Key Laboratory of Natural Medicines of the Changbai Mountain,Ministry of Education,Yanbian University,Yanji,P.R.China
折叠

摘要

关键词

cell-cell cross-talk/NOD-like receptor protein(NLRP3)inflammasome/ovalbumin(OVA)stimulation/toll-like receptor 4(TLR4)/P2X7R synergy

分类

医药卫生

引用本文复制引用

Guangxing Li,Ruobai Liu,Chang Xu,Jianing Yang,Yilan Song,Li Li,Jingzhi Jiang,Liangchang Li,Chongyang Wang,Guanghai Yan..Polydatin alleviates mitochondrial damage and apoptosis of lung epithelial cells by inhibiting toll-like receptor 4-dependent macrophage activation in asthma[J].Animal Models and Experimental Medicine,2026,9(1):P.89-102,14.

基金项目

National Natural Science Foundation of China,Grant/Award Number:82260007 （）

Jilin Province Health Commission,Grant/Award Number:2024A062 （）

Jilin Provincial Department of Education,Grant/Award Number:JJKH20240698KJ （）

Jilin Province Science and Technology Department,Grant/Award Number:20240404025ZP and 20240602100RC。（）

Animal Models and Experimental Medicine

ISSN：2096-5451

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