北京中医药大学学报2026，Vol.49Issue(2)：149-156,8.DOI:10.3969/j.issn.1006-2157.2026.02.001
从孙络与微血管相关性探析虫类药在经皮冠状动脉介入术后心绞痛中的应用
Exploring the application of insect-based drugs in angina pectoris after percutaneous coronary intervention from the perspective of the correlation between Sun collaterals and microvessels
摘要
Abstract
Angina pectoris after percutaneous coronary intervention(PCI)is a common clinical syndrome following surgical treatment of coronary heart diseases.Traditional Chinese medicine(TCM)has unique advantages in improving angina symptoms,reducing attack frequency,and enhancing quality of life.TCM Sun collaterals and modern medical microvessels are highly consistent in anatomical distribution,physiological functions,and pathological manifestations,jointly forming the terminal network of qi and blood perfusion.Based on the correlation between Sun collaterals and microvessels,the core pathogenesis of post-PCI angina is considered"obstructed Sun collaterals and blocked heart meridians",with specific manifestations as follows:Sun collaterals deficiency with stagnation,treated by warming and nourishing with insect-based drugs to nourish collaterals and resolve stagnation;Sun collaterals blocked by blood stasis,with blood stagnation obstructing Xuanfu(skin pores or micro-orifices),treated by eliminating blood stasis with insect-based drugs to dredge Sun collaterals and regulate opening-closing;Sun collaterals of cold coagulation,Yang deficiency and Yin turbidity obstruction,treated by activating Yang with insect-based drugs to dissipate Yin turbidity and relieve obstruction;Sun collaterals spasm due to collateral deficiency and stirring of wind,causing pain,treated by calming wind with insect-based drugs to relieve spasm and pain.By integrating TCM and Western medicine theories,this study provides a new interpretation of pathogenesis at the"Sun collaterals-microvessels"level and a precise insect-based treatment for post-PCI angina,enriches the clinical application of collateral disease theory,and offers new ideas for improving patient prognosis.关键词
经皮冠状动脉介入术后心绞痛/孙络/微血管/虫类药/络病理论Key words
angina pectoris after percutaneous coronary intervention/Sun collaterals/microvessels/insect-based drugs/collateral disease theory分类
医药卫生引用本文复制引用
王宇婷,宁博,王凯,陈红羽,何丽红,张智茹,雷雨轩,王文丽,赵明君..从孙络与微血管相关性探析虫类药在经皮冠状动脉介入术后心绞痛中的应用[J].北京中医药大学学报,2026,49(2):149-156,8.基金项目
国家重点研发计划(No.2018YFC1704204) （No.2018YFC1704204）
陕西省重点研发计划-重点产业创新链(群)项目(No.2024SF-ZDCYL-03-21) （群）
陕西省名中医赵明君传承工作室建设项目(No.2019007) （No.2019007）
陕西省省级院士工作站建设项目-吴以岭院士工作站(No.陕组通字[2019]49号-30) （No.陕组通字[2019]49号-30）
陕西省教育厅重点科研计划项目(No.22JS005) （No.22JS005）
咸阳市重点研发计划项目(No.L2023-ZDYF-SF-047) （No.L2023-ZDYF-SF-047）
秦创原中医药产业创新聚集区项目(No.L2024-QCY-ZYYJJQ-X223) National Key R&D Program of China(No.2018YFC1704204) （No.L2024-QCY-ZYYJJQ-X223）
